DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Ji-Hun | ko |
dc.contributor.author | Kim, Kyunghwan | ko |
dc.contributor.author | Lee, Juno | ko |
dc.contributor.author | Choi, Ji Yu | ko |
dc.contributor.author | Hong, Daewha | ko |
dc.contributor.author | Yang, Sung Ho | ko |
dc.contributor.author | Caruso, Frank | ko |
dc.contributor.author | Lee, Younghoon | ko |
dc.contributor.author | Choi, In-Sung | ko |
dc.date.accessioned | 2015-04-06T07:20:23Z | - |
dc.date.available | 2015-04-06T07:20:23Z | - |
dc.date.created | 2014-11-26 | - |
dc.date.created | 2014-11-26 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.53, no.46, pp.12420 - 12425 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10203/194882 | - |
dc.description.abstract | Single-cell encapsulation promises the cytoprotection of the encased cells against lethal stressors, reminiscent of the sporulation process in nature. However, the development of a cytocompatible method for chemically mimicking the germination process (i.e., shell degradation on-demand) has been elusive, despite the shell degradation being pivotal for the practical use of functional cells as well as for single cell-based biology. We report that an artificial shell, composed of tannic acid (TA) and Fe-III, on individual Saccharomyces cerevisiae controllably degrades on-demand, while protecting the yeast from multiple external aggressors, including UV-C irradiation, lytic enzymes, and silver nanoparticles. Cell division is suppressed by the TA-Fe-III shell, but restored fully upon shell degradation. The formation of a TA-Fe-III shell would provide a versatile tool for achieving the chemical version of sporulation and germination. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | BACILLUS-SUBTILIS | - |
dc.subject | SACCHAROMYCES-CEREVISIAE | - |
dc.subject | SILVER NANOPARTICLES | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | LIVING CELLS | - |
dc.subject | ADHESION | - |
dc.subject | SILICA | - |
dc.subject | SPORES | - |
dc.subject | SHELLS | - |
dc.subject | LAYERS | - |
dc.title | A Cytoprotective and Degradable Metal-Polyphenol Nanoshell for Single-Cell Encapsulation | - |
dc.type | Article | - |
dc.identifier.wosid | 000344649900001 | - |
dc.identifier.scopusid | 2-s2.0-84918820680 | - |
dc.type.rims | ART | - |
dc.citation.volume | 53 | - |
dc.citation.issue | 46 | - |
dc.citation.beginningpage | 12420 | - |
dc.citation.endingpage | 12425 | - |
dc.citation.publicationname | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.doi | 10.1002/anie.201405905 | - |
dc.contributor.localauthor | Lee, Younghoon | - |
dc.contributor.localauthor | Choi, In-Sung | - |
dc.contributor.nonIdAuthor | Kim, Kyunghwan | - |
dc.contributor.nonIdAuthor | Lee, Juno | - |
dc.contributor.nonIdAuthor | Yang, Sung Ho | - |
dc.contributor.nonIdAuthor | Caruso, Frank | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | artificial spores | - |
dc.subject.keywordAuthor | cytoprotection | - |
dc.subject.keywordAuthor | encapsulation | - |
dc.subject.keywordAuthor | organic-inorganic hybrid composites | - |
dc.subject.keywordAuthor | tannic acid | - |
dc.subject.keywordPlus | BACILLUS-SUBTILIS | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
dc.subject.keywordPlus | SILVER NANOPARTICLES | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | LIVING CELLS | - |
dc.subject.keywordPlus | ADHESION | - |
dc.subject.keywordPlus | SILICA | - |
dc.subject.keywordPlus | SPORES | - |
dc.subject.keywordPlus | SHELLS | - |
dc.subject.keywordPlus | LAYERS | - |
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