DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Beom Jin | ko |
dc.contributor.author | Park, Taegyun | ko |
dc.contributor.author | Moon, Hee Chul | ko |
dc.contributor.author | Park, So-Young | ko |
dc.contributor.author | Hong, Daewha | ko |
dc.contributor.author | Ko, Eun Hyea | ko |
dc.contributor.author | Kim, Ji Yup | ko |
dc.contributor.author | Hong, Jong Wook | ko |
dc.contributor.author | Han, Sang Woo | ko |
dc.contributor.author | Kim, Yang-Gyun | ko |
dc.contributor.author | Choi, In-Sung | ko |
dc.date.accessioned | 2015-04-06T06:03:48Z | - |
dc.date.available | 2015-04-06T06:03:48Z | - |
dc.date.created | 2014-12-30 | - |
dc.date.created | 2014-12-30 | - |
dc.date.created | 2014-12-30 | - |
dc.date.issued | 2014-12 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.53, no.52, pp.14443 - 14446 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10203/194770 | - |
dc.description.abstract | Chemical encapsulation of microbes in three-dimensional polymeric microcapsules promises various applications, such as cell therapy and biosensors, and provides a basic platform for studying microbial communications. However, the cytoprotection of microbes in the microcapsules against external aggressors has been a major challenge in the field of microbial microencapsulation, because ionotropic hydrogels widely used for microencapsulation swell uncontrollably, and are physicochemically labile. Herein, we developed a simple polydopamine coating for obtaining cytoprotective capability of the alginate capsule that encapsulated Saccharomyces cerevisiae. The resulting alginate/polydopamine core/shell capsule was mechanically tough, prevented gel swelling and cell leakage, and increased resistance against enzymatic attack and UV-C irradiation. We believe that this multifunctional core/shell structure will provide a practical tool for manipulating microorganisms inside the microcapsules. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Cytoprotective Alginate/Polydopamine Core/Shell Microcapsules in Microbial Encapsulation | - |
dc.type | Article | - |
dc.identifier.wosid | 000346485800024 | - |
dc.identifier.scopusid | 2-s2.0-84919629050 | - |
dc.type.rims | ART | - |
dc.citation.volume | 53 | - |
dc.citation.issue | 52 | - |
dc.citation.beginningpage | 14443 | - |
dc.citation.endingpage | 14446 | - |
dc.citation.publicationname | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.doi | 10.1002/anie.201408454 | - |
dc.contributor.localauthor | Han, Sang Woo | - |
dc.contributor.localauthor | Choi, In-Sung | - |
dc.contributor.nonIdAuthor | Park, So-Young | - |
dc.contributor.nonIdAuthor | Kim, Yang-Gyun | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | cytoprotection | - |
dc.subject.keywordAuthor | encapsulation | - |
dc.subject.keywordAuthor | gels | - |
dc.subject.keywordAuthor | nanostructures | - |
dc.subject.keywordAuthor | polydopamine | - |
dc.subject.keywordPlus | NEURAL INTERFACES | - |
dc.subject.keywordPlus | LIVING CELLS | - |
dc.subject.keywordPlus | ALGINATE | - |
dc.subject.keywordPlus | COATINGS | - |
dc.subject.keywordPlus | BACTERIA | - |
dc.subject.keywordPlus | IMMOBILIZATION | - |
dc.subject.keywordPlus | PROBIOTICS | - |
dc.subject.keywordPlus | CHITOSAN | - |
dc.subject.keywordPlus | POLYMER | - |
dc.subject.keywordPlus | ISLETS | - |
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