DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Juno | ko |
dc.contributor.author | Choi, Jinsu | ko |
dc.contributor.author | Park, Ji-Hun | ko |
dc.contributor.author | Kim, Mihee | ko |
dc.contributor.author | Hong, Daewha | ko |
dc.contributor.author | Cho, Hyeoncheol | ko |
dc.contributor.author | Yang, Sung Ho | ko |
dc.contributor.author | Choi, Insung S. | ko |
dc.date.accessioned | 2015-03-26T08:45:59Z | - |
dc.date.available | 2015-03-26T08:45:59Z | - |
dc.date.created | 2014-09-15 | - |
dc.date.created | 2014-09-15 | - |
dc.date.issued | 2014-07 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.53, no.31, pp.8056 - 8059 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10203/194191 | - |
dc.description.abstract | The cytoprotective coating of physicochemically labile mammalian cells with a durable material has potential applications in cell-based sensors, cell therapy, and regenerative medicine, as well as providing a platform for fundamental single-cell studies in cell biology. In this work, HeLa cells in suspension were individually coated with silica in a cytocompatible fashion through bioinspired silicification. The silica coating greatly enhanced the resistance of the HeLa cells to enzymatic attack by trypsin and the toxic compound poly(allylamine hydrochloride), while suppressing cell division in a controlled fashion. This bioinspired cytocompatible strategy for single-cell coating was also applied to NIH 3T3 fibroblasts and Jurkat cells. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | DIATOM BIOSILICA | - |
dc.subject | CHLORELLA CELLS | - |
dc.subject | GENE DELIVERY | - |
dc.subject | LIVING CELLS | - |
dc.subject | FUNCTIONALIZATION | - |
dc.subject | POLYMERS | - |
dc.subject | ENCAPSULATION | - |
dc.subject | CYTOTOXICITY | - |
dc.subject | VIABILITY | - |
dc.subject | DESIGN | - |
dc.title | Cytoprotective Silica Coating of Individual Mammalian Cells through Bioinspired Silicification | - |
dc.type | Article | - |
dc.identifier.wosid | 000340520700010 | - |
dc.identifier.scopusid | 2-s2.0-84905365748 | - |
dc.type.rims | ART | - |
dc.citation.volume | 53 | - |
dc.citation.issue | 31 | - |
dc.citation.beginningpage | 8056 | - |
dc.citation.endingpage | 8059 | - |
dc.citation.publicationname | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.doi | 10.1002/anie.201402280 | - |
dc.contributor.localauthor | Choi, Insung S. | - |
dc.contributor.nonIdAuthor | Lee, Juno | - |
dc.contributor.nonIdAuthor | Choi, Jinsu | - |
dc.contributor.nonIdAuthor | Cho, Hyeoncheol | - |
dc.contributor.nonIdAuthor | Yang, Sung Ho | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | bioinorganic chemistry | - |
dc.subject.keywordAuthor | cell coating | - |
dc.subject.keywordAuthor | cytoprotection | - |
dc.subject.keywordAuthor | nanostructures | - |
dc.subject.keywordAuthor | silica | - |
dc.subject.keywordPlus | DIATOM BIOSILICA | - |
dc.subject.keywordPlus | CHLORELLA CELLS | - |
dc.subject.keywordPlus | GENE DELIVERY | - |
dc.subject.keywordPlus | LIVING CELLS | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | POLYMERS | - |
dc.subject.keywordPlus | ENCAPSULATION | - |
dc.subject.keywordPlus | CYTOTOXICITY | - |
dc.subject.keywordPlus | VIABILITY | - |
dc.subject.keywordPlus | DESIGN | - |
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