New advances in CMV and immunosenescence

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dc.contributor.authorSansoni, Paoloko
dc.contributor.authorVescovini, Rosannako
dc.contributor.authorFagnoni, Francesco F.ko
dc.contributor.authorAkbar, Arneko
dc.contributor.authorArens, Ramonko
dc.contributor.authorChiu, Yen-Lingko
dc.contributor.authorCicin-Sain, Lukako
dc.contributor.authorDechanet-Merville, Julieko
dc.contributor.authorDerhovanessian, Evelynako
dc.contributor.authorFerrando-Martinez, Sarako
dc.contributor.authorFranceschi, Claudioko
dc.contributor.authorFrasca, Danielako
dc.contributor.authorFuloep, Tamasko
dc.contributor.authorFurman, Davidko
dc.contributor.authorGkrania-Klotsas, Effrossyniko
dc.contributor.authorGoodrum, Feliciako
dc.contributor.authorGrubeck-Loebenstein, Beatrixko
dc.contributor.authorHurme, Mikkoko
dc.contributor.authorKern, Florianko
dc.contributor.authorLilleri, Danieleko
dc.contributor.authorLopez-Botet, Miguelko
dc.contributor.authorMaier, Andrea B.ko
dc.contributor.authorMarandu, Thomasko
dc.contributor.authorMarchant, Arnaudko
dc.contributor.authorMathei, Catharinako
dc.contributor.authorMoss, Paulko
dc.contributor.authorMuntasell, Aurako
dc.contributor.authorRemmerswaal, Ester B. M.ko
dc.contributor.authorRiddell, Natalie E.ko
dc.contributor.authorRothe, Kathrinko
dc.contributor.authorSauce, Delphineko
dc.contributor.authorShin, Eui-Cheolko
dc.contributor.authorSimanek, Amanda M.ko
dc.contributor.authorSmithey, Megan J.ko
dc.contributor.authorSoderberg-Naucler, Ceciliako
dc.contributor.authorSolana, Rafaelko
dc.contributor.authorThomas, Paul G.ko
dc.contributor.authorvan Lier, Reneko
dc.contributor.authorPawelec, Grahamko
dc.contributor.authorNikolich-Zugich, Jankoko
dc.date.accessioned2014-08-29T02:52:17Z-
dc.date.available2014-08-29T02:52:17Z-
dc.date.created2014-06-17-
dc.date.created2014-06-17-
dc.date.issued2014-07-
dc.identifier.citationEXPERIMENTAL GERONTOLOGY, v.55, pp.54 - 62-
dc.identifier.issn0531-5565-
dc.identifier.urihttp://hdl.handle.net/10203/189024-
dc.description.abstractImmunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiological studies suggest that persistent Cytomegalovirus (CMV) infection is associated with accelerated aging of the immune system and with several age-related diseases. However, current evidence on whether and how human CMV (HCMV) infection is implicated in immunosenescence and in age-related diseases remains incomplete and many aspects of CMV involvement in immune aging remain controversial. The attendees of the 4th International Workshop on "CMV & Immunosenescence", held in Parma, Italy, 25-27th March, 2013, presented and discussed data related to these open questions, which are reported in this commentary.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectCD8(+) T-CELLS-
dc.subjectCYTOMEGALOVIRUS-INFECTION-
dc.subjectAGE-
dc.subjectMORTALITY-
dc.subjectGLIOBLASTOMA-
dc.subjectCOMPARTMENT-
dc.subjectPOPULATION-
dc.subjectSURVIVAL-
dc.subjectTHERAPY-
dc.subjectCD4(+)-
dc.titleNew advances in CMV and immunosenescence-
dc.typeArticle-
dc.identifier.wosid000335929300008-
dc.identifier.scopusid2-s2.0-84898883473-
dc.type.rimsART-
dc.citation.volume55-
dc.citation.beginningpage54-
dc.citation.endingpage62-
dc.citation.publicationnameEXPERIMENTAL GERONTOLOGY-
dc.identifier.doi10.1016/j.exger.2014.03.020-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.localauthorShin, Eui-Cheol-
dc.contributor.nonIdAuthorSansoni, Paolo-
dc.contributor.nonIdAuthorVescovini, Rosanna-
dc.contributor.nonIdAuthorFagnoni, Francesco F.-
dc.contributor.nonIdAuthorAkbar, Arne-
dc.contributor.nonIdAuthorArens, Ramon-
dc.contributor.nonIdAuthorChiu, Yen-Ling-
dc.contributor.nonIdAuthorCicin-Sain, Luka-
dc.contributor.nonIdAuthorDechanet-Merville, Julie-
dc.contributor.nonIdAuthorDerhovanessian, Evelyna-
dc.contributor.nonIdAuthorFerrando-Martinez, Sara-
dc.contributor.nonIdAuthorFranceschi, Claudio-
dc.contributor.nonIdAuthorFrasca, Daniela-
dc.contributor.nonIdAuthorFuloep, Tamas-
dc.contributor.nonIdAuthorFurman, David-
dc.contributor.nonIdAuthorGkrania-Klotsas, Effrossyni-
dc.contributor.nonIdAuthorGoodrum, Felicia-
dc.contributor.nonIdAuthorGrubeck-Loebenstein, Beatrix-
dc.contributor.nonIdAuthorHurme, Mikko-
dc.contributor.nonIdAuthorKern, Florian-
dc.contributor.nonIdAuthorLilleri, Daniele-
dc.contributor.nonIdAuthorLopez-Botet, Miguel-
dc.contributor.nonIdAuthorMaier, Andrea B.-
dc.contributor.nonIdAuthorMarandu, Thomas-
dc.contributor.nonIdAuthorMarchant, Arnaud-
dc.contributor.nonIdAuthorMathei, Catharina-
dc.contributor.nonIdAuthorMoss, Paul-
dc.contributor.nonIdAuthorMuntasell, Aura-
dc.contributor.nonIdAuthorRemmerswaal, Ester B. M.-
dc.contributor.nonIdAuthorRiddell, Natalie E.-
dc.contributor.nonIdAuthorRothe, Kathrin-
dc.contributor.nonIdAuthorSauce, Delphine-
dc.contributor.nonIdAuthorSimanek, Amanda M.-
dc.contributor.nonIdAuthorSmithey, Megan J.-
dc.contributor.nonIdAuthorSoderberg-Naucler, Cecilia-
dc.contributor.nonIdAuthorSolana, Rafael-
dc.contributor.nonIdAuthorThomas, Paul G.-
dc.contributor.nonIdAuthorvan Lier, Rene-
dc.contributor.nonIdAuthorPawelec, Graham-
dc.contributor.nonIdAuthorNikolich-Zugich, Janko-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorImmunosenescence-
dc.subject.keywordAuthorCytomegalovirus infection-
dc.subject.keywordAuthorImmune homeostasis-
dc.subject.keywordAuthorPathologies of aging-
dc.subject.keywordAuthorVirus-host interaction-
dc.subject.keywordPlusCD8(+) T-CELLS-
dc.subject.keywordPlusCYTOMEGALOVIRUS-INFECTION-
dc.subject.keywordPlusAGE-
dc.subject.keywordPlusMORTALITY-
dc.subject.keywordPlusGLIOBLASTOMA-
dc.subject.keywordPlusCOMPARTMENT-
dc.subject.keywordPlusPOPULATION-
dc.subject.keywordPlusSURVIVAL-
dc.subject.keywordPlusTHERAPY-
dc.subject.keywordPlusCD4(+)-
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