DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Nam Hee | ko |
dc.contributor.author | Ko, Minsu | ko |
dc.contributor.author | Choi, Insung | ko |
dc.contributor.author | Yun, Wan Soo | ko |
dc.date.accessioned | 2013-08-08T06:01:54Z | - |
dc.date.available | 2013-08-08T06:01:54Z | - |
dc.date.created | 2013-06-18 | - |
dc.date.created | 2013-06-18 | - |
dc.date.issued | 2013-04 | - |
dc.identifier.citation | BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.34, no.4, pp.1035 - 1038 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.uri | http://hdl.handle.net/10203/174779 | - |
dc.description.abstract | Rolling circle amplification (RCA) of DNA on an aligned-carbon nanotube (a-CNT) surface was electrically interfaced by the a-CNT based filed effect transistor (FET). Since the electric conductance of the a-CNT will be dependent upon its local electric environment, the electric conductance of the FET is expected to give a very distinctive signature of the surface reaction along with this isothermal DNA amplification of the RCA. The a-CNT was initially grown on the quartz wafer with the patterned catalyst by chemical vapor deposition and transferred onto a flexible substrate after the formation of electrodes. After immobilization of a primer DNA, the rolling circle amplification was induced on chip with the a-CNT based FET device. The electric conductance showed a quite rapid increase at the early stage of the surface reaction and then the rate of increase was attenuated to reach a saturated stage of conductance change. It took about an hour to get the conductance saturation from the start of the conductance change. Atomic force microscopy was used as a complementary tool to support the successful amplification of DNA on the device surface. We hope that our results contribute to the efforts in the realization of a reliable nanodevice-based measurement of biologically or clinically important molecules. | - |
dc.language | English | - |
dc.publisher | KOREAN CHEMICAL SOC | - |
dc.subject | ELECTRONICS | - |
dc.subject | PROTEIN | - |
dc.subject | ARRAYS | - |
dc.title | Direct Electrical Probing of Rolling Circle Amplification on Surface by Aligned-Carbon Nanotube Field Effect Transistor | - |
dc.type | Article | - |
dc.identifier.wosid | 000318748000004 | - |
dc.identifier.scopusid | 2-s2.0-84877769132 | - |
dc.type.rims | ART | - |
dc.citation.volume | 34 | - |
dc.citation.issue | 4 | - |
dc.citation.beginningpage | 1035 | - |
dc.citation.endingpage | 1038 | - |
dc.citation.publicationname | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.identifier.doi | 10.5012/bkcs.2013.34.4.1035 | - |
dc.contributor.localauthor | Choi, Insung | - |
dc.contributor.nonIdAuthor | Lee, Nam Hee | - |
dc.contributor.nonIdAuthor | Ko, Minsu | - |
dc.contributor.nonIdAuthor | Yun, Wan Soo | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Electric probing | - |
dc.subject.keywordAuthor | Rolling circle amplification | - |
dc.subject.keywordAuthor | Aligned-carbon nanotube | - |
dc.subject.keywordAuthor | Nanobiosensor | - |
dc.subject.keywordPlus | ELECTRONICS | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | ARRAYS | - |
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