Label-free and naked eye detection of PNA/DNA hybridization using enhancement of gold nanoparticles

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Utilizing a gold enhancement process after inducing electrostatic interaction between positively charged gold nanoparticles and negatively charged target DNA hybridized to neutral PNA capture probes, a new method for label-free detection of DNA was developed and successfully applied to detect H5-type DNA.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2010
Language
English
Article Type
Article
Keywords

ELECTRICAL DETECTION; DNA DETECTION; PROBES

Citation

CHEMICAL COMMUNICATIONS, v.46, no.19, pp.3315 - 3317

ISSN
1359-7345
DOI
10.1039/b926940a
URI
http://hdl.handle.net/10203/173637
Appears in Collection
CH-Journal Papers(저널논문)
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