Showing results 1 to 31 of 31
A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing Tong, Yaojun; Jorgensen, Tue S.; Whitford, Christopher M.; Weber, Tilmann; Lee, Sang Yup, NATURE COMMUNICATIONS, v.12, no.1, pp.5206, 2021-09 |
antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters Weber, Tilmann; Blin, Kai; Duddela, Srikanth; Krug, Daniel; Kim, Hyun Uk; Bruccoleri, Robert; Lee, Sang Yup; et al, NUCLEIC ACIDS RESEARCH, v.43, no.W1, pp.W237 - W243, 2015-07 |
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification Blin, Kai; Wolf, Thomas; Chevrette, Marc G.; Lu, Xiaowen; Schwalen, Christopher J.; Kautsar, Satria A.; Duran, Hernando G. Suarez; et al, NUCLEIC ACIDS RESEARCH, v.45, no.W1, pp.W36 - W41, 2017-07 |
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline Blin, Kai; Shaw, Simon; Steinke, Katharina; Villebro, Rasmus; Ziemert, Nadine; Lee, Sang Yup; Medema, Marnix H.; et al, NUCLEIC ACIDS RESEARCH, v.47, no.W1, pp.W81 - W87, 2019-07 |
Automating Cloning by Natural Transformation Jiang, Xinglin; Palazzotto, Emilia; Wybraniec, Ewa; Munro, Lachlan Jake; Zhang, Haibo; Kell, Douglas B.; Weber, Tilmann; et al, ACS SYNTHETIC BIOLOGY, v.9, no.12, pp.3228 - 3235, 2020-11 |
Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters Gren, Tetiana; Whitford, Christopher M.; Mohite, Omkar S.; Jørgensen, Tue S.; Kontou, Eftychia E.; Nielsen, Julie B.; Lee, Sang Yup; et al, SCIENTIFIC REPORTS, v.11, no.1, pp.18301, 2021-09 |
Comparative analysis of Streptomyces strains’ metabolism using genome- scale metabolic models Lee, Byungtae; Mohite, Omkar; Kwon, Mun Su; Weber, Tilmann; Lee, Sang Yup; Kim, Hyun Uk, IIMENA SYMPOSIUM 2023, Technical University of Denmark, 2023-09-25 |
CRISPR-Cas9 Based Engineering of Actinomycetal Genomes Tong, Yaojun; Charusanti, Pep; Zhang, Lixin; Weber, Tilmann; Lee, Sang Yup, ACS SYNTHETIC BIOLOGY, v.4, no.9, pp.1020 - 1029, 2015-09 |
CRISPR-Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes Tong, Yaojun; Whitford, Christopher M.; Blin, Kai; Jorgensen, Tue S.; Weber, Tilmann; Lee, Sang Yup, NATURE PROTOCOLS, v.15, no.8, pp.2470 - 2502, 2020-08 |
CRISPR/Cas-based genome engineering in natural product discovery Tong, Yaojun; Weber, Tilmann; Lee, Sang Yup, NATURAL PRODUCT REPORTS, v.36, no.9, pp.1262 - 1280, 2019-09 |
CRISPy-web: An online resource to design sgRNAs for CRISPR applications Blin, Kai; Pedersen, Lasse Ebdrup; Weber, Tilmann; Lee, Sang Yup, SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, v.1, no.2, pp.118 - 121, 2016-06 |
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens Jiang, Xinglin; Ellabaan, Mostafa M. Hashim; Charusanti, Pep; Munck, Christian; Blin, Kai; Tong, Yaojun; Weber, Tilmann; et al, NATURE COMMUNICATIONS, v.8, 2017-06 |
Distribution of ε-Poly-l-Lysine Synthetases in Coryneform Bacteria Isolated from Cheese and Human Skin Jiang, Xinglin; Radko, Yulia; Gren, Tetiana; Palazzotto, Emilia; Jorgensen, Tue Sparholt; Cheng, Tao; Xian, Mo; et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, v.87, no.10, pp.1 - 8, 2021-05 |
Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions Robertsen, Helene L.; Musiol-Kroll, Ewa M.; Ding, Ling; Laiple, Kristina J.; Hofeditz, Torben; Wohlleben, Wolfgang; Lee, Sang Yup; et al, SCIENTIFIC REPORTS, v.8, 2018-02 |
Genome-Scale Metabolic Reconstruction of Actinomycetes for Antibiotics Production Mohite, Omkar S.; Weber, Tilmann; Kim, Hyun Uk; Lee, Sang Yup, BIOTECHNOLOGY JOURNAL, v.14, no.1, 2019-01 |
Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST Tong, Yaojun; Whitford, Christopher M.; Robertsen, Helene L.; Blin, Kai; Jorgensen, Tue S.; Klitgaard, Andreas K.; Gren, Tetiana; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.116, no.41, pp.20366 - 20375, 2019-10 |
Metabolic analysis of 242 Streptomyces strains using genome-scale metabolic models Lee, Byung Tae; Mohite, Omkar; Kwon, Mun Su; Lee, Sang Yup; Weber, Tilmann; Kim, Hyun Uk, Metabolic Engineering 15, American Institute of Chemical Engineers (AIChE), 2023-06-11 |
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes Weber, Tilmann; Charusanti, Pep; Musiol-Kroll, Ewa Maria; Jiang, Xinglin; Tong, Yaojun; Kim, Hyun Uk; Lee, Sang-Yup, TRENDS IN BIOTECHNOLOGY, v.33, no.1, pp.15 - 26, 2015-01 |
Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites Kim, Hyun Uk; Charusanti, Pep; Lee, Sang Yup; Weber, Tilmann, NATURAL PRODUCT REPORTS, v.33, no.8, pp.933 - 941, 2016-08 |
Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII Musiol-Kroll, Ewa M.; Zubeil, Florian; Schafhauser, Thomas; Haertner, Thomas; Kulik, Andreas; McArthur, John; Koryakina, Irina; et al, ACS SYNTHETIC BIOLOGY, v.6, no.3, pp.421 - 427, 2017-03 |
Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII Musiol-Kroll, Ewa M.; Zubeil, Florian; Schafhauser, Thomas; Haertner, Thomas; Kulik, Andreas; McArthur, John; Koryakina, Irina; et al, ACS SYNTHETIC BIOLOGY, v.6, no.3, pp.421 - 427, 2017-03 |
Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast Jakociunas, Tadas; Klitgaard, Andreas K.; Kontou, Eftychia Eva; Nielsen, Julie Bang; Thomsen, Emil; Romero-Suarez, David; Blin, Kai; et al, SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, v.5, no.1, pp.11 - 18, 2020-03 |
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters Blin, Kai; Kim, Hyun Uk; Medema, Marnix H.; Weber, Tilmann, BRIEFINGS IN BIOINFORMATICS, v.20, no.4, pp.1103 - 1113, 2019-07 |
Recent development of computational resources for new antibiotics discovery Kim, Hyun Uk; Blin K.; Lee, Sang Yup; Weber, Tilmann, CURRENT OPINION IN MICROBIOLOGY, v.39, pp.113 - 120, 2017-10 |
Synthetic biology and metabolic engineering of actinomycetes for natural product discovery Palazzotto, Emilia; Tong, Yaojun; Lee, Sang Yup; Weber, Tilmann, BIOTECHNOLOGY ADVANCES, v.37, no.6, pp.107366, 2019-11 |
Systematic investigation of the metabolism of Streptomyces strains through a pan-reactome analysis Lee, Byungtae; Mohite Omkar S; Kwon, Mun Su; Weber, Tilmann; Lee, Sang Yup; Kim, Hyun Uk, 9th Metabolic Pathway Analysis Conference, MPA 2023, Metabolic Pathway Analysis (MPA), 2023-07-26 |
Systems Analysis of Highly Multiplexed CRISPR-Base Editing in Streptomycetes Whitford, Christopher M.; Gren, Tetiana; Palazzotto, Emilia; Lee, Sang Yup; Tong, Yaojun; Weber, Tilmann, ACS SYNTHETIC BIOLOGY, v.12, no.8, pp.2353 - 2366, 2023-07 |
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters Blin, Kai; Andreu, Victoria Pascal; de los Santos, Emmanuel L. C.; Del Carratore, Francesco; Lee, Sang Yup; Medema, Marnix H.; Weber, Tilmann, NUCLEIC ACIDS RESEARCH, v.47, no.D1, pp.D625 - D630, 2019-01 |
The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters Blin, Kai; Medema, Marnix H.; Kottmann, Renzo; Lee, Sang Yup; Weber, Tilmann, NUCLEIC ACIDS RESEARCH, v.45, no.D1, pp.D555 - D559, 2017-01 |
The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production Weber, Tilmann; Kim, Hyun Uk, SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, v.1, no.2, pp.69 - 79, 2016-06 |
Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites Production Robertsen, Helene Lunde; Weber, Tilmann; Kim, Hyun Uk; Lee, Sang Yup, BIOTECHNOLOGY JOURNAL, v.13, no.1, 2018-01 |
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