Identification of a structural motif of 23S rRNA interacting with 5S rRNA

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dc.contributor.authorKo, Jko
dc.contributor.authorLee, Younghoonko
dc.contributor.authorPark, Iko
dc.contributor.authorCho, Bko
dc.date.accessioned2010-01-08T07:13:02Z-
dc.date.available2010-01-08T07:13:02Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2001-11-
dc.identifier.citationFEBS LETTERS, v.508, no.3, pp.300 - 304-
dc.identifier.issn0014-5793-
dc.identifier.urihttp://hdl.handle.net/10203/16236-
dc.description.abstractTo identify RNA motifs interacting with 5S rRNA, a systematic evolution of ligands by exponential enrichment experiment was applied. Some of the resulting RNA aptamers contained a consensus sequence similar to the sequence in the loop region of helix 89 of 23S rRNA. We show that the synthetic helix 89 RNA motif indeed interacted with 5S rRNA and that the region around loop B of 5S rRNA was involved in this interaction. These results suggest the presence of a novel RNA-RNA interaction between 23S rRNA and 5S rRNA which may play an important role in the ribosome function. (C) 2001 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.-
dc.languageEnglish-
dc.language.isoen_USen
dc.publisherELSEVIER SCIENCE BV-
dc.subjectESCHERICHIA-COLI RIBOSOME-
dc.subjectCROSS-LINKS-
dc.subjectANGSTROM RESOLUTION-
dc.subjectLOOP-IV-
dc.subjectRNA-
dc.subjectSUBUNIT-
dc.subjectENVIRONMENT-
dc.subjectDOMAIN-
dc.titleIdentification of a structural motif of 23S rRNA interacting with 5S rRNA-
dc.typeArticle-
dc.identifier.wosid000172416300004-
dc.identifier.scopusid2-s2.0-0035941128-
dc.type.rimsART-
dc.citation.volume508-
dc.citation.issue3-
dc.citation.beginningpage300-
dc.citation.endingpage304-
dc.citation.publicationnameFEBS LETTERS-
dc.identifier.doi10.1016/S0014-5793(01)03068-X-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.localauthorLee, Younghoon-
dc.contributor.nonIdAuthorKo, J-
dc.contributor.nonIdAuthorPark, I-
dc.contributor.nonIdAuthorCho, B-
dc.type.journalArticleArticle-
dc.subject.keywordAuthor5S rRNA-
dc.subject.keywordAuthorsystematic evolution of ligands by exponential enrichment-
dc.subject.keywordAuthoraptamer-
dc.subject.keywordAuthor23S rRNA-
dc.subject.keywordPlusESCHERICHIA-COLI RIBOSOME-
dc.subject.keywordPlusCROSS-LINKS-
dc.subject.keywordPlusANGSTROM RESOLUTION-
dc.subject.keywordPlusLOOP-IV-
dc.subject.keywordPlusRNA-
dc.subject.keywordPlusSUBUNIT-
dc.subject.keywordPlusENVIRONMENT-
dc.subject.keywordPlusDOMAIN-
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