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College of Life Science and Bioengineering(생명과학기술대학)Dept. of Biological Sciences(생명과학과)BS-Journal Papers(저널논문)

siRNA Conjugate Delivery Systems

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dc.contributor.authorJeong, Ji Hoonko
dc.contributor.authorMok, Hyejungko
dc.contributor.authorOh, Yu-Kyoungko
dc.contributor.authorPark, Tae Gwanko
dc.date.accessioned2009-11-20T05:17:45Z-
dc.date.available2009-11-20T05:17:45Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2009-11-
dc.identifier.citationBIOCONJUGATE CHEMISTRY, v.20, no.1, pp.5 - 14-
dc.identifier.issn1043-1802-
dc.identifier.urihttp://hdl.handle.net/10203/12990-
dc.description.abstractSmall interfering RNA (siRNA) has been chemically conjugated to a variety of bioactive molecules, lipids, polymers, peptides, and inorganic nanostructured materials to enhance their pharmacokinetic behavior, cellular uptake, target specificity, and safety. To efficiently deliver siRNAs to the target cells and tissues, many different siRNA bioconjugates were synthesized and characterized, and their gene silencing efficiencies were tested in vitro and in vivo. In this review, recent developments of siRNA bioconjugates are summarized.-
dc.description.sponsorshipMinistry of Health and Welfare, and the National Research Laboratory program from the Ministry of Education, and Science and Technology, Republic of Korea.en
dc.languageEnglish-
dc.language.isoen_USen
dc.publisherAmer Chemical Soc-
dc.subjectPOLYELECTROLYTE COMPLEX MICELLES-
dc.subjectCELL-PENETRATING PEPTIDES-
dc.subjectSMALL INTERFERING RNA-
dc.subjectPOLY(ETHYLENE GLYCOL)-SIRNA CONJUGATE-
dc.subjectTAT-DEPENDENT TRANSACTIVATION-
dc.subjectCATIONIC FUSOGENIC PEPTIDE-
dc.subjectCULTURED-MAMMALIAN-CELLS-
dc.subjectINNATE IMMUNE-RESPONSE-
dc.subjectTARGETING IN-VIVO-
dc.subjectINTRACELLULAR DELIVERY-
dc.titlesiRNA Conjugate Delivery Systems-
dc.typeArticle-
dc.identifier.wosid000262659700002-
dc.identifier.scopusid2-s2.0-61849162695-
dc.type.rimsART-
dc.citation.volume20-
dc.citation.issue1-
dc.citation.beginningpage5-
dc.citation.endingpage14-
dc.citation.publicationnameBIOCONJUGATE CHEMISTRY-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.localauthorPark, Tae Gwan-
dc.contributor.nonIdAuthorJeong, Ji Hoon-
dc.contributor.nonIdAuthorOh, Yu-Kyoung-
dc.type.journalArticleReview-
dc.subject.keywordPlusPOLYELECTROLYTE COMPLEX MICELLES-
dc.subject.keywordPlusCELL-PENETRATING PEPTIDES-
dc.subject.keywordPlusSMALL INTERFERING RNA-
dc.subject.keywordPlusPOLY(ETHYLENE GLYCOL)-SIRNA CONJUGATE-
dc.subject.keywordPlusTAT-DEPENDENT TRANSACTIVATION-
dc.subject.keywordPlusCATIONIC FUSOGENIC PEPTIDE-
dc.subject.keywordPlusCULTURED-MAMMALIAN-CELLS-
dc.subject.keywordPlusINNATE IMMUNE-RESPONSE-
dc.subject.keywordPlusTARGETING IN-VIVO-
dc.subject.keywordPlusINTRACELLULAR DELIVERY-
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