Surface stabilization of diblock PEG-PLGA micelles by polymerization of N-vinyl-2-pyrrolidone
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | park, t.g | - |
| dc.contributor.author | Kim, H.K | - |
| dc.date.accessioned | 2009-09-07T08:03:09Z | - |
| dc.date.available | 2009-09-07T08:03:09Z | - |
| dc.date.issued | 2002 | - |
| dc.identifier.citation | Macromolecular Rapid Communications, Vol.23, No.1, pp.26-31 | en |
| dc.identifier.issn | 1022-1336 | - |
| dc.identifier.uri | http://hdl.handle.net/10203/11048 | - |
| dc.description.abstract | This paper presents a new approach to improving the physical stability of biodegradable poly-(ethylene glycol)-block-poly[(DL-lactic acid)-co-(glycolic acid)] (PEG-PLGA) micelles. A hydroxyl-terminated PEG monomethacrylate (PEGmer) macroinitiator was used to prepare a methacrylate-end-capped PEG-PLGA diblock copolymer by the ring-opening polymerization of D,L-lactide and glycolide. The surface-exposed methacrylate groups in the shell layer of the micelles can be polymerized with N-vinyl-2-pyrrolidone. The resulting micelles show substantially enhanced stability. | en |
| dc.description.sponsorship | the Center for Advanced Functional Polymers (KAIST), Korea. | en |
| dc.language.iso | en_US | en |
| dc.publisher | John Wiley & Sons | en |
| dc.subject | biodegradable | en |
| dc.subject | micelles | en |
| dc.subject | PEG | en |
| dc.subject | PLGA | en |
| dc.title | Surface stabilization of diblock PEG-PLGA micelles by polymerization of N-vinyl-2-pyrrolidone | en |
| dc.type | Article | en |
| dc.identifier.doi | 10.1002/1521-3927(20020101)23:1<26::AID-MARC26>3.0.CO;2-I | - |
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