Showing results 1 to 18 of 18
A human protein hydroxylase that accepts D-residues![]() Choi, Hwanho; Hardy, Adam P.; Leissing, Thomas M.; Chowdhury, Rasheduzzaman; Nakashima, Yu; Ge, Wei; Markoulides, Marios; et al, COMMUNICATIONS CHEMISTRY, v.3, no.1, 2020-05 |
Application of Fragment-Based de Novo Design to the Discovery of Selective Picomolar Inhibitors of Glycogen Synthase Kinase-3 Beta Park, Hwangseo; Shin, Yongje; Kim, Jinhee; Hong, Sungwoo, JOURNAL OF MEDICINAL CHEMISTRY, v.59, no.19, pp.9018 - 9034, 2016-10 |
Computational Design and Discovery of Nanomolar Inhibitors of I kappa B Kinase beta Park, Hwangseo; Shin, Yong Je; Choe, Hyeonjeong; Hong, Sung-Woo, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.1, pp.337 - 348, 2015-01 |
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.293 - 299, 2016-02 |
Discovery of EGF Receptor Inhibitors That Are Selective for the d746-750/T790M/C797S Mutant through Structure-Based de Novo Design Park, Hwangseo; Jung, Hoi Yun; Mah, Shinmee; Hong, Sungwoo, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.56, no.26, pp.7634 - 7638, 2017-06 |
Discovery of Low Micromolar Dual Inhibitors for Wild Type and L1196M Mutant of Anaplastic Lymphoma Kinase through Structure-Based Virtual Screening Shin, Saemina; Mah, Shinmee; Hong, Sungwoo; Park, Hwangseo, JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.56, no.4, pp.802 - 810, 2016-04 |
Discovery of MEK/PI3K dual inhibitor via structure-based virtual screening Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.15, pp.4946 - 4950, 2012-08 |
Discovery of Picomolar ABL Kinase Inhibitors Equipotent for Wild Type and T315I Mutant via Structure-Based de Novo Design Park, Hwangseo; Hong, Seunghee; Kim, Jinhee; Hong, Sungwoo, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.135, no.22, pp.8227 - 8237, 2013-06 |
Identification of common inhibitors of wild-type and T315I mutant of BCR-ABL through the parallel structure-based virtual screening Park, Hwangseo; Hong, Seunghee; Hong, Sungwoo, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, v.26, no.8, pp.983 - 992, 2012-08 |
Nocodazole is a High-Affinity Ligand for the Cancer-Related Kinases ABL, c-KIT, BRAF, and MEK Park, Hwangseo; Hong, Seunghee; Hong, Sungwoo, CHEMMEDCHEM, v.7, no.1, pp.53 - 56, 2012-01 |
Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors Park, Hwangseo; Jeong, Yujeong; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.22, no.2, pp.1027 - 1030, 2012-01 |
Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors Park, Hwangseo; Lee, So Young; Lee, Suhyun; Hong, Sungwoo, ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.26, pp.4644 - 4655, 2014-06 |
Structure-based de novo design and synthesis of aminothiazole-based p38 MAP kinase inhibitors Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.18, pp.3784 - 3787, 2015-09 |
Structure-Based Virtual Screening and De Novo Design of PIM1 Inhibitors with Anticancer Activity from Natural Products![]() Park, Hwangseo; Jeon, Jinwon; Kim, Kewon; Choi, Soyeon; Hong, Sungwoo, PHARMACEUTICALS, v.14, no.3, 2021-03 |
Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S Mutant of Leucine-Rich Repeat Kinase 2 Park, Hwangseo; Kim, Taeho; Kim, Kewon; Jang, Ahyoung; Hong, Sungwoo, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.21, pp.12825, 2022-11 |
Structure-based virtual screening approach to the discovery of p38 MAP kinase inhibitors Choi, Hwanho; Park, Ho Jeong; Shin, Jong Chul; Ko, Hyun Sun; Lee, Jung Kyun; Lee, Soyoung; Park, Hwangseo; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.6, pp.2195 - 2199, 2012-03 |
Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton's Tyrosine Kinase Kim, Taeho; Kim, Kewon; Park, Inyoung; Hong, Sungwoo; Park, Hwangseo, JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.62, no.18, pp.4500 - 4511, 2022-09 |
Virtual screening and biochemical evaluation to identify new inhibitors of mammalian target of rapamycin (mTOR) Park, Hwangseo; Choe, Hyeonjeong; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.24, no.3, pp.835 - 838, 2014-02 |
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