Graph-theoretical identification of pathways for biochemical reactions

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A rigorous method for identifying biochemical reaction or metabolic pathways through its systematic synthesis has been established. The current method for synthesizing networks of metabolic pathways follows the general framework of a highly exacting combinatorial method. The method is capable of generating not only all combinatorially independent, feasible reaction networks only once, but also those combinations of independent pathways. A case study involving the conversion of glucose to pyruvate with 14 elementary reactions illustrates the efficiency and efficacy of the method. All the results have been obtained with a PC (Pentium-III 550 MHz, 256 MB RAM) within 1 s.
Publisher
KLUWER ACADEMIC PUBL
Issue Date
2001-10
Language
English
Article Type
Article
Keywords

METABOLIC REACTION NETWORKS; OPTIMIZATION

Citation

BIOTECHNOLOGY LETTERS, v.23, no.19, pp.1551 - 1557

ISSN
0141-5492
URI
http://hdl.handle.net/10203/10497
Appears in Collection
CBE-Journal Papers(저널논문)
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