Viable capture and release of cancer cells in human whole blood

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dc.contributor.authorDoh, Ilko
dc.contributor.authorYoo, Hwan-ilko
dc.contributor.authorCho, Young-Hoko
dc.contributor.authorLee, Jinseonko
dc.contributor.authorKim, Hong Kwanko
dc.contributor.authorKim, Jhingookko
dc.date.accessioned2013-03-13T00:56:34Z-
dc.date.available2013-03-13T00:56:34Z-
dc.date.created2012-10-09-
dc.date.created2012-10-09-
dc.date.issued2012-07-
dc.identifier.citationAPPLIED PHYSICS LETTERS, v.101, no.4-
dc.identifier.issn0003-6951-
dc.identifier.urihttp://hdl.handle.net/10203/104053-
dc.description.abstractWe present viable cancer cell isolation devices utilizing the physical properties of cells. The tapered slit structure is proposed to isolate cancer cells from blood cells and collect them by reversed flow. From the experimental study using the spiked cancer cells in human whole blood, we verified the capability of the present cancer cell isolation chip in terms of capture efficiency, viability, and release rate. The viable cancer cells obtained from the present chip can be used for the further applications of cancer diagnosis, treatment monitoring, and new target drug development for cancer stem cells. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4737936]-
dc.languageEnglish-
dc.publisherAMER INST PHYSICS-
dc.subjectCIRCULATING TUMOR-CELLS-
dc.subjectBREAST-CANCER-
dc.subjectPERIPHERAL-BLOOD-
dc.subjectEPITHELIAL-CELLS-
dc.subjectSTEM-CELLS-
dc.subjectDEVICE-
dc.subjectIDENTIFICATION-
dc.subjectENUMERATION-
dc.subjectRELEVANCE-
dc.subjectSIZE-
dc.titleViable capture and release of cancer cells in human whole blood-
dc.typeArticle-
dc.identifier.wosid000306944700112-
dc.identifier.scopusid2-s2.0-84864447601-
dc.type.rimsART-
dc.citation.volume101-
dc.citation.issue4-
dc.citation.publicationnameAPPLIED PHYSICS LETTERS-
dc.identifier.doi10.1063/1.4737936-
dc.contributor.localauthorCho, Young-Ho-
dc.contributor.nonIdAuthorLee, Jinseon-
dc.contributor.nonIdAuthorKim, Hong Kwan-
dc.contributor.nonIdAuthorKim, Jhingook-
dc.type.journalArticleArticle-
dc.subject.keywordPlusCIRCULATING TUMOR-CELLS-
dc.subject.keywordPlusBREAST-CANCER-
dc.subject.keywordPlusPERIPHERAL-BLOOD-
dc.subject.keywordPlusEPITHELIAL-CELLS-
dc.subject.keywordPlusSTEM-CELLS-
dc.subject.keywordPlusDEVICE-
dc.subject.keywordPlusIDENTIFICATION-
dc.subject.keywordPlusENUMERATION-
dc.subject.keywordPlusRELEVANCE-
dc.subject.keywordPlusSIZE-
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