Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy

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Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have shown potential as multifunctional nanoparticles for clinical translation because they have been used asmagnetic resonance imaging (MRI) constrast agents in clinic and their features could be easily tailored by including targeting moieties, fluorescence dyes, or therapeutic agents. This review summarizes targeting strategies for construction of multifunctional nanoparticles including magnetic nanoparticles-based theranostic systems, and the various surface engineering strategies of nanoparticles for in vivo applications.
Publisher
IVYSPRING INT PUBL
Issue Date
2012-01
Language
English
Article Type
Review
Citation

THERANOSTICS, v.2, no.1, pp.3 - 44

ISSN
1838-7640
DOI
10.7150/thno.3463
URI
http://hdl.handle.net/10203/103520
Appears in Collection
BS-Journal Papers(저널논문)
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