DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Sung-Hong | ko |
dc.contributor.author | Duong, Timothy Q. | ko |
dc.date.accessioned | 2013-03-12T18:47:44Z | - |
dc.date.available | 2013-03-12T18:47:44Z | - |
dc.date.created | 2012-06-20 | - |
dc.date.created | 2012-06-20 | - |
dc.date.created | 2012-06-20 | - |
dc.date.issued | 2011-06 | - |
dc.identifier.citation | MAGNETIC RESONANCE IN MEDICINE, v.65, no.6, pp.1702 - 1710 | - |
dc.identifier.issn | 0740-3194 | - |
dc.identifier.uri | http://hdl.handle.net/10203/103182 | - |
dc.description.abstract | A new method for imaging magnetization transfer (MT) asymmetry with no separate saturation pulse is proposed in this article. MT effects were generated from sequential two-dimensional balanced steady-state free precession imaging, where interslice MT asymmetry was separated from interslice blood flow and magnetic field inhomogeneity with alternate ascending/descending directional navigation (ALADDIN). Alternate ascending/descending directional navigation provided high-resolution multislice MT asymmetry images within a reasonable imaging time of similar to 3 min. MT asymmetry signals measured with alternate ascending/descending directional navigation were 1-2% of baseline signals (N = 6), in agreement with those from the conventional methods. About 70% of MT asymmetry signals were determined by the first prior slice. The frequency offset ranges in this study were >8 ppm from the water resonance frequency, implying that the MT effects were mostly associated with solid-like macromolecules. Potential methods to make alternate ascending/descending directional navigation feasible for imaging amide proton transfer (similar to 3.5 ppm offset from the water resonance frequency) were discussed. Magn Reson Med 65:1702-1710, 2011. (C)2010 Wiley-Liss, Inc. | - |
dc.language | English | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.title | Alternate Ascending/Descending Directional Navigation Approach for Imaging Magnetization Transfer Asymmetry | - |
dc.type | Article | - |
dc.identifier.wosid | 000291115500020 | - |
dc.identifier.scopusid | 2-s2.0-79958248353 | - |
dc.type.rims | ART | - |
dc.citation.volume | 65 | - |
dc.citation.issue | 6 | - |
dc.citation.beginningpage | 1702 | - |
dc.citation.endingpage | 1710 | - |
dc.citation.publicationname | MAGNETIC RESONANCE IN MEDICINE | - |
dc.identifier.doi | 10.1002/mrm.22568 | - |
dc.contributor.localauthor | Park, Sung-Hong | - |
dc.contributor.nonIdAuthor | Duong, Timothy Q. | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | magnetization transfer | - |
dc.subject.keywordAuthor | magnetization transfer asymmetry | - |
dc.subject.keywordAuthor | balanced steady-state free precession | - |
dc.subject.keywordAuthor | alternate ascending/descending directional navigation | - |
dc.subject.keywordAuthor | amide proton transfer | - |
dc.subject.keywordAuthor | chemical exchange saturation transfer | - |
dc.subject.keywordPlus | SATURATION-TRANSFER CEST | - |
dc.subject.keywordPlus | HUMAN BRAIN | - |
dc.subject.keywordPlus | QUANTITATIVE DESCRIPTION | - |
dc.subject.keywordPlus | TRANSFER CONTRAST | - |
dc.subject.keywordPlus | WATER SATURATION | - |
dc.subject.keywordPlus | MULTISLICE | - |
dc.subject.keywordPlus | RESONANCE | - |
dc.subject.keywordPlus | SEQUENCES | - |
dc.subject.keywordPlus | PEPTIDES | - |
dc.subject.keywordPlus | PROTEINS | - |
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