Synthetic approach to flavanones and flavones via ligand-free palladium(II)-catalyzed conjugate addition of arylboronic acids to chromones

Cited 50 time in webofscience Cited 0 time in scopus
  • Hit : 408
  • Download : 0
The remarkable catalytic effects of Fe(OTf)(3) in the context of the Pd(II)-catalyzed conjugate addition of arylboronic acids to chromones were observed to yield a variety of flavanones under mild conditions. The addition of catalytic amounts of DDQ and KNO2 to the reactions exclusively yielded flavone analogs. The reaction scope for the transformation was fairly broad, affording good yields of a wide range of flavanones and flavones, which are privileged structures in many biologically active compounds.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2012-09
Language
English
Article Type
Article
Keywords

ALPHA,BETA-UNSATURATED KETONES; ASYMMETRIC 1,4-ADDITION; COMPLEX; ACETYLENES; ANNULATION; ALDEHYDES; CHALCONE; CATALYST; IODIDES; AGENTS

Citation

ORGANIC & BIOMOLECULAR CHEMISTRY, v.10, no.36, pp.7305 - 7312

ISSN
1477-0520
DOI
10.1039/c2ob26061a
URI
http://hdl.handle.net/10203/102627
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 50 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0