Mesoporous silica nanoparticles in biomedical applications

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This tutorial review provides an outlook on nanomaterials that are currently being used for theranostic purposes, with a special focus on mesoporous silica nanoparticle (MSNP) based materials. MSNPs with large surface area and pore volume can serve as efficient carriers for various therapeutic agents. The functionalization of MSNPs with molecular, supramolecular or polymer moieties, provides the material with great versatility while performing drug delivery tasks, which makes the delivery process highly controllable. This emerging area at the interface of chemistry and the life sciences offers a broad palette of opportunities for researchers with interests ranging from sol-gel science, the fabrication of nanomaterials, supramolecular chemistry, controllable drug delivery and targeted theranostics in biology and medicine.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2012
Language
English
Article Type
Review
Keywords

DRUG-DELIVERY RATE; CANCER-CELLS; ORGANIC MODIFICATION; CONTROLLED-RELEASE; SURFACE-CHARGE; MCM-41; DOXORUBICIN; NANOCARRIERS; TUMOR; SIZE

Citation

CHEMICAL SOCIETY REVIEWS, v.41, no.7, pp.2590 - 2605

ISSN
0306-0012
DOI
10.1039/c1cs15246g
URI
http://hdl.handle.net/10203/101593
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