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Showing results 184801 to 184820 of 275509

184801
Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors

Park, Hwangseo; Jeong, Yujeong; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.22, no.2, pp.1027 - 1030, 2012-01

184802
Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors

Park, Hwangseo; Lee, So Young; Lee, Suhyun; Hong, Sungwoo, ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.26, pp.4644 - 4655, 2014-06

184803
Structure-based de novo design and synthesis of aminothiazole-based p38 MAP kinase inhibitors

Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.18, pp.3784 - 3787, 2015-09

184804
Structure-based design and efficient synthesis of kinase inhibitors via palladium catalysis = 구조에 기반한 키나아제 저해제의 설계와 팔라듐 촉매 반응을 이용한 효율적인 합성법 연구link

Kim, Jinhee; 김진희; et al, 한국과학기술원, 2016

184805
Structure-based design of flavone-based inhibitors of wild-type and T315I mutant of ABL

Choe, Hyeonjeong; Kim, Jieun; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.23, no.15, pp.4324 - 4327, 2013-08

184806
Structure-based development of novel small-molecule kinase inhibitors and efficient synthesis of frutinone a derivatives = 구조에 기반한 새로운 저분자 키나아제 저해제의 개발과 프루티논 A 유도체의 효율적 합성에 관한 연구link

Shin, Yongje; 신용제; et al, 한국과학기술원, 2017

184807
Structure-based drug discovery using deep neural networks

Kim, Woo Youn, 2019 KSBMB International Conference, KSBMB, 2019-06-05

184808
Structure-based glycoengineering of interferon lambda 4 enhances its productivity and anti-viral potency

Chung, Jae-Hee; Hong, Seon-Hui; Seo, Nari; Kim, Tae-Shin; An, Hyun Joo; Lee, Pedro; Shin, Eui-Cheol; et al, CYTOKINE, v.125, 2020-01

184809
Structure-based Markov random field model for representing evolutionary constraints on functional sites

Jeong, Chan-Seok; Kim, Dongsup, BMC Bioinformatics, v.17, no.1, 2016-02

184810
Structure-based mutational analysis of the active site residues of D-hydantoinase

Cheon, YH; Park, Hee-Sung; Lee, SC; Lee, DE; Kim, Hak-Sung, JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, v.26, no.3-6, pp.217 - 222, 2003-12

184811
Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123

Ann, Sojin; Yoon, Jung Min; Kim, Hanseong; Song, Ji-Joon; Choi, Uhn-soo, ELIFE, v.6, 2017-10

184812
Structure-based protein engineering on potential therapeutic proteins = 치료용 후보단백질의 구조기반 엔지니어링link

Chung, Jae-Hee; Kim, Ho Min; et al, 한국과학기술원, 2019

184813
Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein

Han, Ji-Eun; Kim, Hyun-Jung; Lee, Sang-Chul; Hong, Seung-Pyo; Park, Keun-Wan; Jeon, Young-Ho; Kim, Dong-Sup; et al, PLOS ONE, v.7, no.2, 2012

184814
Structure-based rebuilding of coevolutionary information reveals functional modules in rhodopsin structure

Park, Keun-Wan; Kim, Dong-Sup, BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v.1824, no.12, pp.1484 - 1489, 2012-12

184815
Structure-based strategy for development of novel ALK inhibitor and dual inhibitor of G protein-coupled receptor signaling = 구조 기반 전략을 통한 새로운 역형성 림프종 인산화효소 저해제와 G 단백질 연결 수용체 신호의 이중 저해제 개발에 대한 연구link

Mah, Shinmee; Hong, Sungwoo; et al, 한국과학기술원, 2019

184816
Structure-based studies on the metal binding of two-metal-dependent sugar isomerases

Prabhu, Ponnandy; Thi-Ngoc-Thanh Doan; Tiwari, Manish; Singh, Raushan; Kim, Sun-Chang; Hong, Myoung-Ki; Kang, Yun Chan; et al, FEBS JOURNAL, v.281, no.15, pp.3446 - 3459, 2014-08

184817
Structure-Based Synthesizability Prediction of Crystals Using Partially Supervised Learning

Jang, Jidon; Gu, Geun Ho; Noh, Juhwan; Kim, Juhwan; Jung, Yousung, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.142, no.44, pp.18836 - 18843, 2020-11

184818
Structure-Based Virtual Screening and De Novo Design of PIM1 Inhibitors with Anticancer Activity from Natural Products

Park, Hwangseo; Jeon, Jinwon; Kim, Kewon; Choi, Soyeon; Hong, Sungwoo, PHARMACEUTICALS, v.14, no.3, 2021-03

184819
Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S Mutant of Leucine-Rich Repeat Kinase 2

Park, Hwangseo; Kim, Taeho; Kim, Kewon; Jang, Ahyoung; Hong, Sungwoo, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.21, pp.12825, 2022-11

184820
Structure-based virtual screening approach to the discovery of p38 MAP kinase inhibitors

Choi, Hwanho; Park, Ho Jeong; Shin, Jong Chul; Ko, Hyun Sun; Lee, Jung Kyun; Lee, Soyoung; Park, Hwangseo; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.6, pp.2195 - 2199, 2012-03

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