Researcher Page


Yi, Gwan-Su (이관수) A-7896-2011

Department of Bio and Brain Engineering(바이오및뇌공학과)
Research Area
Computational Systems Biology, Synthetic Biology, medical information

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Solution structure of MUL1-RING domain and its interaction with p53 transactivation domain

Lee, Min-Sung; Lee, Sang-Ok; Lee, Mi-Kyung; et al, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.516, no.2, pp.533 - 539, 2019-08


A novel mechanism of irinotecan targeting MDM2 and Bcl-xL

Lee, Boah; Min, Jeong A.; Nashed, Abdullateef; et al, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.514, no.2, pp.518 - 523, 2019-06


Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation

Kim, So Young; Hong, MiNa; Heo, Seung-Ho; et al, MOLECULAR CARCINOGENESIS, v.57, no.11, pp.1492 - 1506, 2018-11


Prediction of Novel Anoctamin1 (ANO1) Inhibitors Using 3D-QSAR Pharmacophore Modeling and Molecular Docking

Lee, Yoon Hyeok; Yi, Gwan-Suresearcher, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.19, no.10, 2018-10


Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction

Li, Yi; Jung, Nan Young; Yoo, Jae Cheal; et al, BIOMOLECULES & THERAPEUTICS, v.26, no.5, pp.458 - 463, 2018-09


JAB1 regulates CPNE1-related differentiation via direct binding to CPNE1 in HiB5 hippocampal progenitor cells

Yoo, Jae Cheal; Park, Nammi; Choi, Hye Young; et al, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.497, no.1, pp.424 - 429, 2018-02


Copine1 regulates neural stem cell functions during brain development

Kim, Tae Hwan; Sung, Soo-Eun; Yoo, Jae Cheal; et al, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.495, no.1, pp.168 - 173, 2018-01


Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study

Joo, Young Bin; Kim, Yul; Park, Youngho; et al, ARTHRITIS RESEARCH & THERAPY, v.19, 2017-10


14-3-3 gamma regulates Copinel-mediated neuronal differentiation in HiB5 hippocampal progenitor cells

Yoo, Jae Cheal; Park, Nammi; Lee, Boah; et al, EXPERIMENTAL CELL RESEARCH, v.356, no.1, pp.85 - 92, 2017-07


Drug repositioning for enzyme modulator based on human metabolite-likeness

Lee, Yoon Hyeok; Choi, Hojae; Park, Seongyong; et al, BMC BIOINFORMATICS, v.18, no.7, 2017-05


Discovering gene expression signatures responding to tyrosine kinase inhibitor treatment in chronic myeloid leukemia

Cha, Kihoon; Li, Yi; Yi, Gwan-Suresearcher, BMC MEDICAL GENOMICS, v.9, 2016-08


Prediction of scaffold proteins based on protein interaction and domain architectures

Oh, Kimin; Yi, Gwan-Suresearcher, BMC BIOINFORMATICS, v.17, 2016-07


Suppression of 14-3-3 gamma-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells

Lee, Young-Sun; Lee, Jae Kwang; Bae, Yeonju; et al, SCIENTIFIC REPORTS, v.6, 2016-05


Disease association and inter-connectivity analysis of human brain specific co-expressed functional modules

Oh, Kimin; Hwang, Tae-Ho; Cha, Ki Hoon; et al, BIOLOGICAL RESEARCH, v.48, 2015-12


Ubiquitination-dependent degradation of p73 by the mitochondrial E3 ubiquitin ligase Hades

Min, Bumki; Ryu, Jiwon; Chi, Seung-Wook; et al, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.467, no.2, pp.316 - 321, 2015-11


Discovering transnosological molecular basis of human brain diseases using biclustering analysis of integrated gene expression data

Cha, Ki Hoon; Hwang, Taeho; Oh, Kimin; et al, BMC MEDICAL INFORMATICS AND DECISION MAKING, v.15, 2015-05


Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition

Shin, Jae-Sun; Ha, Ji-Hyang; Lee, Dong-Hwa; et al, CELL CYCLE, v.14, no.4, pp.533 - 543, 2015-02


Detection and analysis of disease-associated single nucleotide polymorphism influencing post-translational modification

Kim, Yul; Kang, Chiyong; Min, Bumki; et al, BMC MEDICAL GENOMICS, v.8, 2015


A Conserved Mechanism for Binding of p53 DNA-Binding Domain and Anti-Apoptotic Bcl-2 Family Proteins

Lee, Dong-Hwa; Ha, Ji-Hyang; Kim, Yul; et al, MOLECULES AND CELLS, v.37, no.3, pp.264 - 269, 2014-03


Unique Behavioral Characteristics and microRNA Signatures in a Drug Resistant Epilepsy Model

Moon, Jangsup; Lee, Soon-Tae; Choi, Jiye; et al, PLOS ONE, v.9, no.1, 2014-01

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