Researcher Page


Park, Hee-Sung (박희성) C-2042-2011

Department of Chemistry(화학과)
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Research Area
Biochemistry, Chemical biology, Protein chemistry

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Attomolar detection of extracellular microRNAs released from living prostate cancer cells by a plasmonic nanowire interstice sensor

Yang, Si Yeong; Kim, Hongki; Lee, Kyung Jin; Hwang, Seul Gee; Lim, Eun-Kyung; Jung, Juyeon; Lee, Tae Jae; Park, Hee-Sungresearcher; Kang, Taejoon; Kim, BongsooresearcherROYAL SOC CHEMISTRYNANOSCALE, v.9, no.44, pp.17387 - 17395, 2017-11


Genetic incorporation of N-epsilon-acetyllysine reveals a novel acetylation-sumoylation switch in yeas

Kim, Sang Woo; Lee, Kyung Jin; Kim, Sinil; Kim, Jihyo; Cho, Kyu Kwang; Ro, Hyeon-Su; Park, Hee-SungresearcherELSEVIER SCIENCE BVBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, v.1861, no.11, pp.3030 - 3037, 2017-11


A fluorogenic and red-shifted diphenyl phosphinate-based probe for selective peroxynitrite detection as demonstrated in fixed cells

Mulay, Sandip V.; Kim, Youngsam; Lee, KyungJin; Yudhistira, Tesla; Park, Hee-Sungresearcher; Churchill, David G.researcherROYAL SOC CHEMISTRYNEW JOURNAL OF CHEMISTRY, v.41, no.20, pp.11934 - 11940, 2017-10


Thiomaleimide Functionalization for Selective Biological Fluorescence Detection of Peroxynitrite as Tested in HeLa and RAW 264.7 Cells

Yudhistira, Tesla; Mulay, Sandip V.; Lee, KyungJin; Kim, Youngsam; Park, Hee-Sungresearcher; Churchill, David G.researcherWILEY-V C H VERLAG GMBHCHEMISTRY-AN ASIAN JOURNAL, v.12, no.15, pp.1927 - 1934, 2017-08


Expanding the genetic code of Mus musculus

Han, Songmi; Yang, Aerin; Lee, Soonjang; Lee, Han-Woong; Park, Chan Bae; Park, Hee-SungresearcherNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.8, 2017-02 View PDF (1916kb)


A chemical biology route to site-specific authentic protein modifications

Yang, Aerin; Ha, Sura; Ahn, Jihye; Kim, Rira; Kim, Sungyoon; Lee, Younghoonresearcher; Kim, Jaehoonresearcher; Soell, Dieter; Lee, Hee-Yoonresearcher; Park, Hee-SungresearcherAMER ASSOC ADVANCEMENT SCIENCESCIENCE, v.354, no.6312, pp.623 - 626, 2016-11


Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription

Josefowicz, Steven Z.; Shimada, Miho; Armache, Anja; Li, Charles H.; Miller, Rand M.; Lin, Shu; Yang, Aerin; Dill, Brian D.; Molina, Henrik; Park, Hee-Sungresearcher; Garcia, Benjamin A.; Taunton, Jack; Roeder, Robert G.; Allis, C. DavidCELL PRESSMOLECULAR CELL, v.64, no.2, pp.347 - 361, 2016-10


A robust and quantitative assay platform for multiplexed, high throughput screening of protein kinase inhibitors

Lee, Jieon; Park, Il-Soo; Park, Ginam; Cho, Kyu Kwang; Park, Hee-Sungresearcher; Min, Dal-HeeROYAL SOC CHEMISTRYCHEMICAL COMMUNICATIONS, v.52, no.81, pp.12112 - 12115, 2016-10


Truncated SRA RNA derivatives inhibit estrogen receptor-alpha-mediated transcription

Jung, Euihan; Jang, Seonghui; Lee, Jungmin; Kim, Youngmi; Shin, Heegwon; Park, Hee-Sungresearcher; Lee, YounghoonresearcherSPRINGERMOLECULAR BIOLOGY REPORTS, v.43, no.10, pp.1019 - 1025, 2016-10


Development of background-free tame fluorescent probes for intracellular live cell imaging

Alamudi, Samira Husen; Satapathy, Rudrakanta; Kim, Jihyo; Su, Dongdong; Ren, Haiyan; Das, Rajkumar; Hu, Lingna; Alvarado-Martinez, Enrique; Lee, Jung Yeol; Hoppmann, Christian; Pena-Cabrera, Eduardo; Ha, Hyung-Ho; Park, Hee-Sungresearcher; Wang, Lei; Chang, Young-TaeNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.7, 2016-06


Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway

Seo, Gil Ju; Yang, Aerin; Tan, Brandon; Kim, Sungyoon; Liang, Qiming; Choi, Younho; Yuan, Weiming; Feng, Pinghui; Park, Hee-Sungresearcher; Jung, Jae U.CELL PRESSCELL REPORTS, v.13, no.2, pp.440 - 449, 2015-10 View PDF (2307kb)


Negative regulation of NF-kappa B activity by brain-specific TRIpartite Motif protein 9

Shi, Mude; Cho, Hyelim; Inn, Kyung-Soo; Yang, Aerin; Zhao, Zhen; Liang, Qiming; Versteeg, Gijs A.; Amini-Bavil-Olyaee, Samad; Wong, Lai-Yee; Zlokovic, Berislav V.; Park, Hee-Sungresearcher; Garcia-Sastre, Adolfo; Jung, Jae U.NATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.5, 2014-09 View PDF (1355kb)


Dopamine and Cu+/(2+) Can Induce Oligomerization of alpha-Synuclein in the Absence of Oxygen: Two Types of Oligomerization Mechanisms for alpha-Synuclein and Related Cell Toxicity Studies

Ha, Yong Hwang; Yang, Aerin; Lee, Seyoung; Kim, Kibong; Liew, Hyunjeong; Lee, Sang Hyung; Lee, Ju Eun; Lee, Hong-In; Suh, Yoo-Hun; Park, Hee-Sungresearcher; Churchill, David GresearcherWILEY-BLACKWELLJOURNAL OF NEUROSCIENCE RESEARCH, v.92, no.3, pp.359 - 368, 2014-03


Facile "stop codon" method reveals elevated neuronal toxicity by discrete S87p-alpha-synuclein oligomers

Ha, Yonghwang; Yang, Aerin; Lee, Seyoung; Kim, Kibong; Liew, Hyunjeong; Suh, Yoo-Hun; Park, Hee-Sungresearcher; Churchill, David GresearcherACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.443, no.3, pp.1085 - 1091, 2014-01


A Facile Strategy for Selective Incorporation of Phosphoserine into Histones

Lee, Sangsik; Oh, Seunghee; Yang, Aerin; Kim, Jihyo; Soell, Dieter; Lee, Daeyoupresearcher; Park, Hee-SungresearcherWILEY-V C H VERLAG GMBHANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.22, pp.5771 - 5775, 2013-05


Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis

Kim, Ji-Hyo; Seo, Moon-Hyeong; Lee, Sang-Sik; Cho, Kyu-Kwang; Yang, Ae-Rin; Woo, Kyung-Hwa; Kim, Hak-Sungresearcher; Park, Hee-SungresearcherAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.85, no.3, pp.1468 - 1474, 2013-02


N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo

Umehara, Takuya; Kim, Jihyo; Lee, Sangsik; Guo, Li-Tao; Soell, Dieter; Park, Hee-SungresearcherELSEVIER SCIENCE BVFEBS LETTERS, v.586, no.6, pp.729 - 733, 2012-03


Efficient Single-Molecule Fluorescence Resonance Energy Transfer Analysis by Site-Specific Dual-Labeling of Protein Using an Unnatural Amino Acid

Seo, Moon-Hyeong; Lee, Tae-Sun; Kim, Eun-Kyung; Cho, Young-Lag; Park, Hee-Sungresearcher; Yoon, Tae-Youngresearcher; Kim, Hak-SungresearcherAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.83, no.23, pp.8849 - 8854, 2011-12


Expanding the Genetic Code of Escherichia coli with Phosphoserine

Park, Hee-Sungresearcher; Hohn, MJ; Umehara, T; Guo, LT; Benner, J; Noren, CJ; Rinehart, J; Soll, DAMER ASSOC ADVANCEMENT SCIENCESCIENCE, v.333, no.6046, pp.1151 - 1154, 2011-08


Controlled and Oriented Immobilization of Protein by Site-Specific Incorporation of Unnatural Amino Acid

Seo, Moon-Hyeong; Han, Ji-Eun; Jin, Zongwen; Lee, Dong-Won; Park, Hee-Sungresearcher; Kim, Hak-SungresearcherAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.83, no.8, pp.2841 - 2845, 2011-04

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