Researcher Page


Park, Hee-Sung (박희성) C-2042-2011

Department of Chemistry(화학과)
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Research Area
Biochemistry, Chemical biology, Protein chemistry

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Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription

Josefowicz, Steven Z.; Shimada, Miho; Armache, Anja; Li, Charles H.; Miller, Rand M.; Lin, Shu; Yang, Aerin; Dill, Brian D.; Molina, Henrik; Park, Hee-Sungresearcher; Garcia, Benjamin A.; Taunton, Jack; Roeder, Robert G.; Allis, C. DavidCELL PRESSMOLECULAR CELL, v.64, no.2, pp.347 - 361, 2016-10


Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway

Yang, Aerin; Kim, Sungyoon; Choi, Younho; Feng, Pinghui; Jung, Jae U.; Seo, Gil Ju; Tan, Brandon; Liang, Qiming; Yuan, Weiming; Park, Hee-SungresearcherCELL PRESSCELL REPORTS, v.13, no.2, pp.440 - 449, 2015-10 View PDF (2307kb)


Negative regulation of NF-kappa B activity by brain-specific TRIpartite Motif protein 9

Inn, Kyung-Soo; Wong, Lai-Yee; Liang, Qiming; Garcia-Sastre, Adolfo; Cho, Hyelim; Amini-Bavil-Olyaee, Samad; Zhao, Zhen; Park, Hee-Sungresearcher; Shi, Mude; Versteeg, Gijs A.; Jung, Jae U.; Yang, Aerin; Zlokovic, Berislav V.NATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.5, 2014-09 View PDF (1355kb)


Dopamine and Cu+/(2+) Can Induce Oligomerization of alpha-Synuclein in the Absence of Oxygen: Two Types of Oligomerization Mechanisms for alpha-Synuclein and Related Cell Toxicity Studies

Yang, Aerin; Lee, Sang Hyung; Park, Hee-Sungresearcher; Ha, Yong Hwang; Lee, Seyoung; Kim, Kibong; Lee, Ju Eun; Lee, Hong-In; Suh, Yoo-Hun; Churchill, David Gresearcher; Liew, HyunjeongWILEY-BLACKWELLJOURNAL OF NEUROSCIENCE RESEARCH, v.92, no.3, pp.359 - 368, 2014-03


Facile "stop codon" method reveals elevated neuronal toxicity by discrete S87p-alpha-synuclein oligomers

Lee, Seyoung; Park, Hee-Sungresearcher; Ha, Yonghwang; Liew, Hyunjeong; Kim, Kibong; Churchill, David Gresearcher; Yang, Aerin; Suh, Yoo-HunACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.443, no.3, pp.1085 - 1091, 2014-01


A Facile Strategy for Selective Incorporation of Phosphoserine into Histones

Lee, Daeyoupresearcher; Oh, Seunghee; Yang, Aerin; Kim, Jihyo; Soell, Dieter; Lee, Sangsik; Park, Hee-SungresearcherWILEY-V C H VERLAG GMBHANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.22, pp.5771 - 5775, 2013-05


Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis

Kim, Ji-Hyo; Cho, Kyu-Kwang; Woo, Kyung-Hwa; Yang, Ae-Rin; Seo, Moon-Hyeong; Lee, Sang-Sik; Kim, Hak-Sungresearcher; Park, Hee-SungresearcherAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.85, no.3, pp.1468 - 1474, 2013-02


N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo

Kim, Jihyo; Park, Hee-Sungresearcher; Lee, Sangsik; Umehara, Takuya; Soell, Dieter; Guo, Li-TaoELSEVIER SCIENCE BVFEBS LETTERS, v.586, no.6, pp.729 - 733, 2012-03


Efficient Single-Molecule Fluorescence Resonance Energy Transfer Analysis by Site-Specific Dual-Labeling of Protein Using an Unnatural Amino Acid

Cho, Young-Lag; Park, Hee-Sungresearcher; Yoon, Tae-Youngresearcher; Kim, Hak-Sungresearcher; Lee, Tae-Sun; Seo, Moon-Hyeong; Kim, Eun-KyungAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.83, no.23, pp.8849 - 8854, 2011-12


Expanding the Genetic Code of Escherichia coli with Phosphoserine

Park, Hee-Sungresearcher; Guo, LT; Benner, J; Noren, CJ; Rinehart, J; Hohn, MJ; Soll, D; Umehara, TAMER ASSOC ADVANCEMENT SCIENCESCIENCE, v.333, no.6046, pp.1151 - 1154, 2011-08


Controlled and Oriented Immobilization of Protein by Site-Specific Incorporation of Unnatural Amino Acid

Han, Ji-Eun; Kim, Hak-Sungresearcher; Jin, Zongwen; Lee, Dong-Won; Park, Hee-Sungresearcher; Seo, Moon-HyeongAMER CHEMICAL SOCANALYTICAL CHEMISTRY, v.83, no.8, pp.2841 - 2845, 2011-04


Toward understanding phosphoseryl-tRNA(Cys) formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase

Schnitzbauer, M; Sauerwald, A; Steitz, TA; Park, Hee-Sungresearcher; Kamtekar, S; Soll, D; Hohn, MJNATL ACAD SCIENCESPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.104, no.8, pp.2620 - 2625, 2007-02


Emergence of the universal genetic code imprinted in an RNA record

O'Donoghue, P; Schnitzbauer, M; Park, Hee-Sungresearcher; Hohn, MJ; Soll, DNATL ACAD SCIENCESPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.103, no.48, pp.18095 - 18100, 2006-11


Design and evolution of new catalytic activity with an existing protein scaffold

Mannervik, Bengt; Kim, Hak-Sungresearcher; Lee, Jin Kak; Yoon, Chang No; Park, Hee-Sungresearcher; Nam, Sung-HunAMER ASSOC ADVANCEMENT SCIENCESCIENCE, v.311, no.5760, pp.535 - 538, 2006-01


Evolutionary relationship and application of a superfamily of cyclic amidohydrase enzymes

Kim, Hak-Sungresearcher; Park, Hee-Sungresearcher; Nam, Sung-HunWiley-BlackwellCHEMICAL RECORD, v.5, no.5, pp.298 - 307, 2005-10


Manipulation of the active site loops of D-hydantoinase, a (beta/alpha)(8)-barrel protein, for modulation of the substrate specificity

Kim, Hak-Sungresearcher; Kim, Youngsoo; Cheon, Young-Hoon; Kim, Jin-Hyun; Park, Hee-SungresearcherAMER CHEMICAL SOCBIOCHEMISTRY, v.43, no.23, pp.7413 - 7420, 2004-06


Improving the functional expression of N-carbamoylase by directed evolution using the green fluorescent protein fusion reporter system

Oh, Ki-Hoon; Park, Hee-Sungresearcher; Kim, Hak-SungresearcherElsevier Academic Press IncMETHODS IN ENZYMOLOGY, v.388, pp.187 - 195, 2004-05


Structure-based mutational analysis of the active site residues of D-hydantoinase

Cheon, YH; Park, Hee-Sungresearcher; Lee, SC; Kim, Hak-Sungresearcher; Lee, DEELSEVIER SCIENCE BVJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, v.26, no.3-6, pp.217 - 222, 2003-12


Generation of protein lineages with new sequence spaces by functional salvage screen

Kim, GJ; Cheon, YH; Park, Hee-Sungresearcher; Kim, Hak-Sungresearcher; Park, MSOXFORD UNIV PRESSPROTEIN ENGINEERING, v.14, no.9, pp.647 - 654, 2001-09


Genetic and structural organization of the aminophenol catabolic operon and its implication for evolutionary process

Park, Hee-Sungresearcher; Kim, Hak-SungresearcherAmerican Society for MicrobiologyJOURNAL OF BACTERIOLOGY, v.183, no.17, pp.5074 - 5081, 2001 View PDF (1104kb)

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