Researcher Page

사진

Lim, Dae-Sik (임대식) C-1599-2011 0000-0003-2356-7555

Department
Department of Biological Sciences(생명과학과)
Co-author
Collaboration Network Collaboration Network
Website
http://dlim.kaist.ac.kr/contents/HomePage
Research Area
Hippo signaling, Molecular Oncology, Adult Stem Cell Division and Differentiation

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1

Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcilloma

Lee, Byung Soo; Park, Dong Il; Lee, Da-Hye; Lee, Jeong Eun; Yeo, Min-kyung; Park, Yeon Hee; Lim, Dae Sikresearcher; Choi, Wonyoung; Lee, Da-Hye; Yoo, Geon; Kim, Hanbyul; Kang, Dahyun; Moon, Jae Young; Jung, Sung Soo; Kim, Ju Ock; Cho, Sang Yeon; Park, Hee Sun; Chung, ChaeukACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.491, no.2, pp.493 - 499, 2017-09

2

Mechanical cue-induced YAP instructs Skp2-dependent cell cycle exit and oncogenic signaling

Jang, Won Yul; Kim, Tackhoon; Koo, Ja Seung; Kim, Sang-kyum; Lim, Dae-SikresearcherWILEYEMBO JOURNAL, v.36, no.17, pp.2510 - 2528, 2017-09

3

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

Kim, Jongshin; Kim, Yoo Hyung; Kim, Jaeryung; Park, Do Young; Bae, Hosung; Lee, Da-Hye; Kim, Kyun Hoo; Hong, Seon Pyo; Jang, Seung Pil; Kubota, Yoshiaki; Kwon, Young-Guen; Lim, Dae-Sikresearcher; Koh, Gou YoungresearcherAMER SOC CLINICAL INVESTIGATION INCJOURNAL OF CLINICAL INVESTIGATION, v.127, no.9, pp.3447 - 3467, 2017-09

4

The novel YAP target gene, SGK1, upregulates TAZ activity by blocking GSK3 beta-mediated TAZ destabilization

Yoo, Geon; Kim, Tackhoon; Chung, Chaeuk; Hwang, Deog-Su; Lim, Dae-SikresearcherACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.490, no.3, pp.650 - 656, 2017-08

5

Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival

Robertson, Abigail; Mohamed, Tamer M. A.; El Maadawi, Zeinab; Stafford, Nicholas; Bui, Thuy; Lim, Dae-Sikresearcher; Cartwright, Elizabeth J.; Oceandy, DelvacELSEVIER SCIENCE BVSTEM CELL RESEARCH, v.20, pp.42 - 49, 2017-04 View PDF (1103kb)

6

NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization

Kondo, Naoyuki; Ueda, Yoshihiro; Kita, Toshiyuki; Ozawa, Madoka; Tomiyama, Takashi; Yasuda, Kaneki; Lim, Dae-Sikresearcher; Kinashi, TatsuoAMER SOC MICROBIOLOGYMOLECULAR AND CELLULAR BIOLOGY, v.37, no.8, 2017-04

7

Prostaglandin E-2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice

Kim, Hanbyul; Kim, Minchul; Park, Young-Soo; Park, Intae; Kim, Tackhoon; Yang, Sung-Yeun; Cho, Charles J.; Hwang, DaeHee; Jung, Jin-Hak; Markowitz, Sanford D.; Hwang, Sung Wook; Yang, Suk-Kyun; Lim, Dae-Sikresearcher; Myung, Seung-JaeW B SAUNDERS CO-ELSEVIER INCGASTROENTEROLOGY, v.152, no.3, pp.616 - 630, 2017-02

8

MRTF potentiates TEAD-YAP transcriptional activity causing metastasis

Kim, Tackhoon; Hwang, DaeHee; Lee, Da-Hye; Kim, Jeong-Hwan; Kim, Seon‐Young; Lim, Dae-SikresearcherWILEY-BLACKWELLEMBO JOURNAL, v.36, no.4, pp.520 - 535, 2017-02

9

MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane

Kurz, Angela R. M.; Pruenster, Monika; Rohwedder, Ina; Ramadass, Mahalakshmi; Schaefer, Kerstin; Harrison, Ute; Gouveia, Gabriel; Nussbaum, Claudia; Immler, Roland; Wiessner, Johannes R.; Margraf, Andreas; Lim, Dae-Sikresearcher; Walzog, Barbara; Dietzel, Steffen; Moser, Markus; Klein, Christoph; Vestweber, Dietmar; Haas, Rainer; Catz, Sergio D.; Sperandio, MarkusAMER SOC CLINICAL INVESTIGATION INCJOURNAL OF CLINICAL INVESTIGATION, v.126, no.11, pp.4125 - 4139, 2016-11

10

The E3 ubiquitin ligase CHIP selectively regulates mutant epidermal growth factor receptor by ubiquitination and degradation

Chung, Chaeuk; Yoo, Geon; Kim, Tackhoon; Lee, Dahye; Lee, Choong-Sik; Cha, Hye Rim; Park, Yeon Hee; Moon, Jae Young; Jung, Sung Soo; Kim, Ju Ock; Lee, Jae Cheol; Kim, Sun Young; Park, Hee Sun; Park, Myoungrin; Park, Dong Il; Lim, Dae-Sikresearcher; Jang, Kang Won; Lee, Jeong EunACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.479, no.2, pp.152 - 158, 2016-10

11

The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis

Seo, Eunjeong; Kim, Wan-Young; Hur, Jeongmi; Kim, Hanbyul; Nam, Sun Ah; Choi, Arum; Kim, Yu-Mi; Park, Sang Hee; Chung, Chaeuk; Kim, Jin; Min, Soohong; Myung, Seung-Jae; Lim, Dae-Sikresearcher; Kim, Yong KyunNATURE PUBLISHING GROUPSCIENTIFIC REPORTS, v.6, 2016-08

12

LATS-YAP/TAZ controls lineage specification by regulating TGF beta signaling and Hnf4 alpha expression during liver development

Lee, Da-Hye; Park, Jae Oh; Kim, Tae-Shin; Kim, Sang-Kyum; Kim, Tackhoon; Kim, Minchul; Park, Geonsoo; Kim, Jeong-Hwan; Kuninaka, Shinji; Olson, Eric N.; Saya, Hideyuki; Kim, Seon-Young; Lee, Ho; Lim, Dae-SikresearcherNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.7, 2016-06 View PDF (3509kb)

13

Hippo pathway effector YAP inhibition restores the sensitivity of EGFR-TKI in lung adenocarcinoma having primary or acquired EGFR-TKI resistance

Lee, Jeong Eun; Park, Hee Sun; Lee, Dahye; Yoo, Geon; Kim, Tackhoon; Jeon, Haeyon; Yeo, Min-Kyung; Lee, Choong-Sik; Moon, Jae Young; Jung, Sung Soo; Kim, Ju Ock; Kim, Sun Young; Il Park, Dong; Park, Yeon Hee; Lee, Jae Cheol; Oh, In-Jae; Lim, Dae-Sikresearcher; Chung, ChaeukACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.474, no.1, pp.154 - 160, 2016-05

14

An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2

Park, Geonsoo; Oh, Hyangyee; Kim, Minchul; Kim, Tackhoon; Johnson, Randy L.; Irvine, Kenneth D.; Lim, Dae-SikresearcherIMPACT JOURNALS LLCONCOTARGET, v.7, no.17, pp.24063 - 24075, 2016-04

15

Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2

Park, Changwon; Lee, Tae-Jin; Bhang, Suk Ho; Liu, Fang; Nakamura, Rei; Oladipupo, Sunday S.; Pitha-Rowe, Ian; Capoccia, Benjamin; Choi, Hong Seo; Kim, Tae Min; Urao, Norifumi; Ushio-Fukai, Masuko; Lee, Dongjun; Miyoshi, Hiroyuki; Kim, Byung-Soo; Lim, Dae-Sikresearcher; Apte, Rajendra S.; Ornitz, David M.; Choi, KyungheeLIPPINCOTT WILLIAMS & WILKINSARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, v.36, no.1, pp.86 - 96, 2016-01

16

Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition

Kim, Miju; Kim, Minchul; Park, Seong Jun; Lee, Cheolju; Lim, Dae-SikresearcherWILEY-BLACKWELLEMBO REPORTS, v.17, no.1, pp.64 - 78, 2016-01

17

The SRF-YAP-IL6 axis promotes breast cancer stemness

Kim, Tackhoon; Lim, Dae-SikresearcherTAYLOR & FRANCIS INCCELL CYCLE, v.15, no.10, pp.1311 - 1312, 2016

18

A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness

Kim, Tackhoon; Yang, Suk-Jin; Hwang, Daehee; Song, Jinhoi; Kim, Minchul; Kim, Sang Kyum; Kang, Keunsoo; Ahn, Jaebum; Lee, Daeyoupresearcher; Kim, Mi-youngresearcher; Kim, Seyunresearcher; Koo, Ja Seung; Koh, Sang Seok; Kim, Seon-Young; Lim, Dae-SikresearcherNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.6, 2015-12 View PDF (2454kb)

19

Mst2 Controls Bone Homeostasis by Regulating Osteoclast and Osteoblast Differentiation

Lee, Jongwon; Youn, Bang Ung; Kim, Kabsun; Kim, Jung Ha; Lee, Da-Hye; Seong, Semun; Kim, Inyoung; Han, Seung-Hee; Che, Xiangguo; Choi, Je-Yong; Park, Yong-Wook; Kook, Hyun; Kim, Kyung Keun; Lim, Dae-Sikresearcher; Kim, NacksungWILEY-BLACKWELLJOURNAL OF BONE AND MINERAL RESEARCH, v.30, no.9, pp.1597 - 1607, 2015-09

20

Mouse Hepatic Tumor Vascular Imaging by Experimental Selective Angiography

Kim, Sang Kyum; Kim, Honsoul; Koh, Gou Youngresearcher; Lim, Dae-Sikresearcher; Yu, Dae-Yeul; Kim, Man Deuk; Park, Mi-Suk; Lim, Joon SeokPUBLIC LIBRARY SCIENCEPLOS ONE, v.10, no.7, 2015-07 View PDF (3227kb)

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