Researcher Page


Lim, Dae-Sik (임대식) C-1599-2011

Department of Biological Sciences(생명과학과)
Collaboration Network Collaboration Network
Research Area
Hippo signaling, Molecular Oncology, Adult Stem Cell Division and Differentiation

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NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization

Kondo, Naoyuki; Ueda, Yoshihiro; Kita, Toshiyuki; Ozawa, Madoka; Tomiyama, Takashi; Yasuda, Kaneki; Lim, Dae-Sikresearcher; Kinashi, TatsuoAMER SOC MICROBIOLOGYMOLECULAR AND CELLULAR BIOLOGY, v.37, no.8, 2017-04


Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival

Robertson, Abigail; Mohamed, Tamer M. A.; El Maadawi, Zeinab; Stafford, Nicholas; Bui, Thuy; Lim, Dae-Sikresearcher; Cartwright, Elizabeth J.; Oceandy, DelvacELSEVIER SCIENCE BVSTEM CELL RESEARCH, v.20, pp.42 - 49, 2017-04


MRTF potentiates TEAD-YAP transcriptional activity causing metastasis

Kim, Tackhoon; Hwang, DaeHee; Lee, Da-Hye; Kim, Jeong-Hwan; Kim, Seon‐Young; Lim, Dae-SikresearcherWILEY-BLACKWELLEMBO JOURNAL, v.36, no.4, pp.520 - 535, 2017-02


Prostaglandin E-2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice

Kim, Hanbyul; Kim, Minchul; Park, Young-Soo; Park, Intae; Kim, Tackhoon; Yang, Sung-Yeun; Cho, Charles J.; Hwang, DaeHee; Jung, Jin-Hak; Markowitz, Sanford D.; Hwang, Sung Wook; Yang, Suk-Kyun; Lim, Dae-Sikresearcher; Myung, Seung-JaeW B SAUNDERS CO-ELSEVIER INCGASTROENTEROLOGY, v.152, no.3, pp.616 - 630, 2017-02


MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane

Kurz, Angela R. M.; Pruenster, Monika; Rohwedder, Ina; Ramadass, Mahalakshmi; Schaefer, Kerstin; Harrison, Ute; Gouveia, Gabriel; Nussbaum, Claudia; Immler, Roland; Wiessner, Johannes R.; Margraf, Andreas; Lim, Dae-Sikresearcher; Walzog, Barbara; Dietzel, Steffen; Moser, Markus; Klein, Christoph; Vestweber, Dietmar; Haas, Rainer; Catz, Sergio D.; Sperandio, MarkusAMER SOC CLINICAL INVESTIGATION INCJOURNAL OF CLINICAL INVESTIGATION, v.126, no.11, pp.4125 - 4139, 2016-11


The E3 ubiquitin ligase CHIP selectively regulates mutant epidermal growth factor receptor by ubiquitination and degradation

Chung, Chaeuk; Yoo, Geon; Kim, Tackhoon; Lee, Dahye; Lee, Choong-Sik; Cha, Hye Rim; Park, Yeon Hee; Moon, Jae Young; Jung, Sung Soo; Kim, Ju Ock; Lee, Jae Cheol; Kim, Sun Young; Park, Hee Sun; Park, Myoungrin; Park, Dong Il; Lim, Dae-Sikresearcher; Jang, Kang Won; Lee, Jeong EunACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.479, no.2, pp.152 - 158, 2016-10


The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis

Seo, Eunjeong; Kim, Wan-Young; Hur, Jeongmi; Kim, Hanbyul; Nam, Sun Ah; Choi, Arum; Kim, Yu-Mi; Park, Sang Hee; Chung, Chaeuk; Kim, Jin; Min, Soohong; Myung, Seung-Jae; Lim, Dae-Sikresearcher; Kim, Yong KyunNATURE PUBLISHING GROUPSCIENTIFIC REPORTS, v.6, 2016-08


LATS-YAP/TAZ controls lineage specification by regulating TGF beta signaling and Hnf4 alpha expression during liver development

Lee, Da-Hye; Park, Jae Oh; Kim, Tae-Shin; Kim, Sang-Kyum; Kim, Tackhoon; Kim, Minchul; Park, Geonsoo; Kim, Jeong-Hwan; Kuninaka, Shinji; Olson, Eric N.; Saya, Hideyuki; Kim, Seon-Young; Lee, Ho; Lim, Dae-SikresearcherNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.7, 2016-06 View PDF (3509kb)


Hippo pathway effector YAP inhibition restores the sensitivity of EGFR-TKI in lung adenocarcinoma having primary or acquired EGFR-TKI resistance

Lee, Jeong Eun; Park, Hee Sun; Lee, Dahye; Yoo, Geon; Kim, Tackhoon; Jeon, Haeyon; Yeo, Min-Kyung; Lee, Choong-Sik; Moon, Jae Young; Jung, Sung Soo; Kim, Ju Ock; Kim, Sun Young; Il Park, Dong; Park, Yeon Hee; Lee, Jae Cheol; Oh, In-Jae; Lim, Dae-Sikresearcher; Chung, ChaeukACADEMIC PRESS INC ELSEVIER SCIENCEBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.474, no.1, pp.154 - 160, 2016-05


An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2

Park, Geonsoo; Oh, Hyangyee; Kim, Minchul; Kim, Tackhoon; Johnson, Randy L.; Irvine, Kenneth D.; Lim, Dae-SikresearcherIMPACT JOURNALS LLCONCOTARGET, v.7, no.17, pp.24063 - 24075, 2016-04


Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2

Park, Changwon; Lee, Tae-Jin; Bhang, Suk Ho; Liu, Fang; Nakamura, Rei; Oladipupo, Sunday S.; Pitha-Rowe, Ian; Capoccia, Benjamin; Choi, Hong Seo; Kim, Tae Min; Urao, Norifumi; Ushio-Fukai, Masuko; Lee, Dongjun; Miyoshi, Hiroyuki; Kim, Byung-Soo; Lim, Dae-Sikresearcher; Apte, Rajendra S.; Ornitz, David M.; Choi, KyungheeLIPPINCOTT WILLIAMS & WILKINSARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, v.36, no.1, pp.86 - 96, 2016-01


Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition

Kim, Miju; Kim, Minchul; Park, Seong Jun; Lee, Cheolju; Lim, Dae-SikresearcherWILEY-BLACKWELLEMBO REPORTS, v.17, no.1, pp.64 - 78, 2016-01


The SRF-YAP-IL6 axis promotes breast cancer stemness

Kim, Tackhoon; Lim, Dae-SikresearcherTAYLOR & FRANCIS INCCELL CYCLE, v.15, no.10, pp.1311 - 1312, 2016


A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness

Kim, Tackhoon; Yang, Suk-Jin; Hwang, Daehee; Song, Jinhoi; Kim, Minchul; Kim, Sang Kyum; Kang, Keunsoo; Ahn, Jaebum; Lee, Daeyoupresearcher; Kim, Mi-youngresearcher; Kim, Seyunresearcher; Koo, Ja Seung; Koh, Sang Seok; Kim, Seon-Young; Lim, Dae-SikresearcherNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.6, 2015-12 View PDF (2454kb)


Mst2 Controls Bone Homeostasis by Regulating Osteoclast and Osteoblast Differentiation

Lee, Jongwon; Youn, Bang Ung; Kim, Kabsun; Kim, Jung Ha; Lee, Da-Hye; Seong, Semun; Kim, Inyoung; Han, Seung-Hee; Che, Xiangguo; Choi, Je-Yong; Park, Yong-Wook; Kook, Hyun; Kim, Kyung Keun; Lim, Dae-Sikresearcher; Kim, NacksungWILEY-BLACKWELLJOURNAL OF BONE AND MINERAL RESEARCH, v.30, no.9, pp.1597 - 1607, 2015-09


Mouse Hepatic Tumor Vascular Imaging by Experimental Selective Angiography

Kim, Sang Kyum; Kim, Honsoul; Koh, Gou Youngresearcher; Lim, Dae-Sikresearcher; Yu, Dae-Yeul; Kim, Man Deuk; Park, Mi-Suk; Lim, Joon SeokPUBLIC LIBRARY SCIENCEPLOS ONE, v.10, no.7, 2015-07 View PDF (3227kb)


Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila

Choi, Se Kyu; Lim, Dae-Sikresearcher; Chung, JongkyeongPUBLIC LIBRARY SCIENCEPLOS GENETICS, v.11, no.5, 2015-05 View PDF (6208kb)


Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

Mo, Jung-Soo; Meng, Zhipeng; Kim, Young Chul; Park, Hyun Woo; Hansen, Carsten Gram; Kim, Soohyun; Lim, Dae-Sikresearcher; Guan, Kun-LiangNATURE PUBLISHING GROUPNATURE CELL BIOLOGY, v.17, no.4, pp.500 - +, 2015-04


Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

Kim, Minchul; Kim, Taekhoon; Johnson, Randy L.; Lim, Dae-SikresearcherCELL PRESSCELL REPORTS, v.11, no.2, pp.270 - 282, 2015-04 View PDF (3527kb)


The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis

Kim, Miju; Kim, Minchul; Lee, Mi-Sun; Kim, Cheol-Hee; Lim, DSNATURE PUBLISHING GROUPNATURE COMMUNICATIONS, v.5, 2014-11 View PDF (2746kb)

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