In this study, the tensile properties of carbon fiber reinforced polymer (CFRP) composites with different resin compositions were investigated in order to develop advanced composite materials for cryogenic use. Thermo-mechanical cyclic loading (up to 6 cycles) was applied to CFRP unidirectional laminate specimens from room temperature to -150 degrees C. Tensile tests were then performed at -150 degrees C using an environmental test chamber. In addition, matrix-dominant properties such as the transverse and in-plane shear characteristics of each composite model were measured at -150 degrees C to examine the effects of resin formulation on their interfacial properties. The tensile tests showed that the composite models with large amounts of bisphenol-A epoxy and CTBN modified rubber in their resin composition had good mechanical performance at cryogenic temperatures (CTs).