DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhang, Yu | ko |
dc.contributor.author | Yang, Mo | ko |
dc.contributor.author | Park, Ji-Ho | ko |
dc.contributor.author | Singelyn, Jennifer | ko |
dc.contributor.author | Ma, Huiqing | ko |
dc.contributor.author | Sailor, Michael J. | ko |
dc.contributor.author | Ruoslahti, Erkki | ko |
dc.contributor.author | Ozkan, Mihrimah | ko |
dc.contributor.author | Ozkan, Cengiz | ko |
dc.date.accessioned | 2013-03-11T07:22:36Z | - |
dc.date.available | 2013-03-11T07:22:36Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2009-09 | - |
dc.identifier.citation | SMALL, v.5, no.17, pp.1990 - 1996 | - |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.uri | http://hdl.handle.net/10203/98640 | - |
dc.description.abstract | Surface-charge measurements of mammalian cells in terms of Zeta potential are demonstrated as a useful biological characteristic in identifying cellular interactions with specific nanomaterials. A theoretical model of the changes in Zeta potential of cells after incubation with nanoparticles is established to predict the possible patterns of Zeta-potential change to reveal the binding and internalization effects. The experimental results show a distinct Pattern of Zeta potential change that allows the discrimination of human normal breast epithelial cells (MCF-10A) from human cancer breast epithelial cells (MCF-7) when the cells are incubated with dextran coated iron oxide nanoparticles that contain tumor-homing F3 peptides, where the tumor-homing F3 peptide specifically bound to nucleolin receptors that are overexpressed in cancer breast cells. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | MRI CONTRAST AGENTS | - |
dc.subject | IN-VIVO | - |
dc.subject | SUPERPARAMAGNETIC NANOPARTICLES | - |
dc.subject | MAGNETIC-RESONANCE | - |
dc.subject | ENDOTHELIAL-CELLS | - |
dc.subject | EPITHELIAL-CELLS | - |
dc.subject | HOMING PEPTIDES | - |
dc.subject | MESSENGER-RNA | - |
dc.subject | CANCER-CELLS | - |
dc.subject | NUCLEOLIN | - |
dc.title | A Surface-Charge Study on Cellular-Uptake Behavior of F3-Peptide-Conjugated Iron Oxide Nanoparticles | - |
dc.type | Article | - |
dc.identifier.wosid | 000270160600013 | - |
dc.identifier.scopusid | 2-s2.0-70349097300 | - |
dc.type.rims | ART | - |
dc.citation.volume | 5 | - |
dc.citation.issue | 17 | - |
dc.citation.beginningpage | 1990 | - |
dc.citation.endingpage | 1996 | - |
dc.citation.publicationname | SMALL | - |
dc.identifier.doi | 10.1002/smll.200900520 | - |
dc.contributor.localauthor | Park, Ji-Ho | - |
dc.contributor.nonIdAuthor | Zhang, Yu | - |
dc.contributor.nonIdAuthor | Yang, Mo | - |
dc.contributor.nonIdAuthor | Singelyn, Jennifer | - |
dc.contributor.nonIdAuthor | Ma, Huiqing | - |
dc.contributor.nonIdAuthor | Sailor, Michael J. | - |
dc.contributor.nonIdAuthor | Ruoslahti, Erkki | - |
dc.contributor.nonIdAuthor | Ozkan, Mihrimah | - |
dc.contributor.nonIdAuthor | Ozkan, Cengiz | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | cellular uptake | - |
dc.subject.keywordAuthor | F3 peptide | - |
dc.subject.keywordAuthor | iron oxide nanoparticles | - |
dc.subject.keywordAuthor | Zeta potential | - |
dc.subject.keywordPlus | MRI CONTRAST AGENTS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | SUPERPARAMAGNETIC NANOPARTICLES | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE | - |
dc.subject.keywordPlus | ENDOTHELIAL-CELLS | - |
dc.subject.keywordPlus | EPITHELIAL-CELLS | - |
dc.subject.keywordPlus | HOMING PEPTIDES | - |
dc.subject.keywordPlus | MESSENGER-RNA | - |
dc.subject.keywordPlus | CANCER-CELLS | - |
dc.subject.keywordPlus | NUCLEOLIN | - |
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