The Effect of Protectants and pH Changes on the Cellular Growth and Succinic Acid Yield of Mannheimia succiniciproducens LPK7

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The harmful effects of succinic acid and oxidative stress on cell growth were determined during batch fermentation with Mannheimia succiniciproducens LPK7, a powerful succinic acid-producing strain, and conditions were optimized to minimize these effects. In terms of toxicity, the cell concentration decreased as the concentration of succinic acid increased. By changing the pH from 6.5 to 7 during fermentation, the cell concentration increased by about 10%, and the level of succinic acid production was 6% higher than that of the control. In addition, by introducing protectants, the cell concentration increased by about 10%, and the level of succinic acid produced was increased by 3%.
Publisher
KOREAN SOC MICROBIOLOGY BIOTECHNOLOGY
Issue Date
2010-12
Language
English
Article Type
Article
Citation

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.20, no.12, pp.1677 - 1680

ISSN
1017-7825
DOI
10.4014/jmb.1003.03032
URI
http://hdl.handle.net/10203/97934
Appears in Collection
CBE-Journal Papers(저널논문)
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