In this paper, solar-powered, multi-scale, vibration-impedance sensor node on Imote2 platform is presented for hybrid structural health monitoring (SHM) in cable-stayed bridge. In order to achieve the objective, the following approaches are proposed. Firstly, vibration- and impedance-based hybrid SHM methods are briefly described. Secondly, the multi-scale vibration and impedance sensor node on Imote2-platform is presented on the design of hardware components and embedded software for vibration- and impedance-based SHM. In this approach, a solar-powered energy harvesting is implemented for autonomous operation of the smart sensor nodes. Finally, the feasibility and practicality of the smart sensor-based SHM system is evaluated on a full-scale cable-stayed bridge, Hwamyung Bridge in Korea. Successful level of wireless communication and solar-power supply for smart sensor nodes are verified. Also, vibration and impedance responses measured from the target bridge which experiences various weather conditions are examined for the robust long-term monitoring capability of the smart sensor system.