Label-Free Electrochemical DNA Detection Based on Electrostatic Interaction between DNA and Ferrocene Dendrimers

Cited 3 time in webofscience Cited 0 time in scopus
  • Hit : 543
  • Download : 313
A label-free DNA detection method was developed for a simple electrochemical DNA sensor with a short assay time Self-assembled monolayers of peptide nucleic acid were used as a probe on gold electrodes The formation of the self-assembled monolayers on the gold electrodes was successfully checked by means of cyclic voltammetry The target DNA, hybridized with peptide nucleic acid, can be detected by the anodic peak current of ferrocene dendrimers, which interact electrostatically with the target DNA This anodic peak current was measured by square wave voltammetry at 0 3 V to decrease the detection limit on the order of the nanomolar concentrations As a result, the label-free electrochemical DNA sensor can detect the target DNA in concentrations ranging from 1 nM to 1 mu M with a detection limit of 1 nM
Publisher
KOREAN CHEMICAL SOC
Issue Date
2010-11
Language
English
Article Type
Article
Keywords

SELF-ASSEMBLED MONOLAYER; TIN OXIDE ELECTRODES; ION-CHANNEL SENSORS; GOLD ELECTRODES; BIOSENSORS; AMPLIFICATION; LIPOSOMES; ANTIBODY; POLYMER; SURFACE

Citation

BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.31, no.11, pp.3099 - 3102

ISSN
0253-2964
DOI
10.5012/bkcs.2010.31.11.3099
URI
http://hdl.handle.net/10203/94147
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
000284794100008.pdf(337.15 kB)Download
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 3 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0