In this paper, a computationally efficient stack-based iterative detection algorithm is proposed for V-BLAST systems. To minimize the receiver's efforts as much as possible, the proposed scheme employs iterative tree search for complexity reduction and storage saving. After an M-ary tree structure by QR decomposition of channel matrix is constructed, the full tree depth is divided into the first depth and the remaining ones. At tree depth of one, the proposed algorithm finds M candidate symbols. Based on these symbols, it iteratively searches the remaining symbols at second-to-last depth, until finding an optimal symbol sequence. Simulation results demonstrate that the proposed algorithm yields the performance close to that of sphere detection (SD) with significant saving in complexity and storage.