Isolation and characterization of epidermal mucus from Hirudo nipponia

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The epidermal organ of the leech contains a complex glycoprotein molecule of mucus, The mucus excreted from annelids plays significant role in protection against desiccation and parasites. Mucus: from the Korean native leech, H. nipponia, was investigated for biochemical characteristics for possible development oi bismaterials of cosmetic and pharmaceutical agents. The leech skin mucus was heavily glycosylated mucin-like protein with a high molecular weight comprised 80% carbohydrate and 20% protein, Threonine, serine, and glycine were the major components of the isolated protein and these accounted for 50% of total amino acids. The carbohydrate portion contained glucosamine. galactosamine, galactose, glucose, mannose and sialic acid in oligosaccharide form linked with threonine and serine residues of the glycoprotein.
Publisher
BIOCHEMICAL SOC REPUBLIC KOREA
Issue Date
1996-05
Language
English
Article Type
Article
Keywords

MUCIN; GLYCOPROTEINS; OLIGOSACCHARIDES; PURIFICATION

Citation

JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, v.29, no.3, pp.248 - 252

ISSN
1225-8687
URI
http://hdl.handle.net/10203/77679
Appears in Collection
BS-Journal Papers(저널논문)
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