An anisotropic hardening description is proposed on the basis of the Generalized Isotropic Hardening (GIH) rule. The key concept of the GIH rule is that any proper stress state inside or on an yield surface can be the homologic center of isotropic hardening. A concrete constitutive relationship was formulated by utilizing a simple hardening function. For verification, three sets of triaxial test results obtained from drained and undrained tests on overconsolidated clays and K-0 consolidated clays were evaluated. Consequently, it was determined that the proposed model can represent any plastic deformation in reverse loading.