EXTRACTION OF INDOLE ALKALOIDS FROM CATHARANTHUS ROSEUS BY USING SUPERCRITICAL CARBON DIOXIDE

Indole alkaloids, particularly vindoline and catharanthine, were extracted from the leaves of Catharanthus roseus by supercritical extraction with CO(2). The contents of vindoline and catharanthine in the extracts were determined by HPLC and identified by LC/MS. About 52 %(w/w) of the initial vindoline content, 1.5 mg vindoline/g dry wt leaves, was recovered after extracting this material for 10 h with the CO(2) flow rate of 400 ml/min at 40 degrees C and 150 bar. Vindoline concentration in the extract was 67 %(w/w).
Publisher
SPRINGER
Issue Date
1992-03
Language
ENG
Citation

BIOTECHNOLOGY TECHNIQUES, v.6, no.2, pp.127 - 130

ISSN
0951-208X
URI
http://hdl.handle.net/10203/62433
Appears in Collection
CBE-Journal Papers(저널논문)
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