Polypeptide for binding to complement protein C5A, and use of same 보체 단백질 C5a와 결합할 수 있는 신규한 폴리펩타이드 및 그 용도

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The present invention relates to novel polypeptide for binding to a complement protein C5a. More particularly, the present invention relates to polypeptide which can be bound to a complement protein C5a and inhibit the activation of same, polynucleotide which codes for the polypeptide, a recombinant vector which comprises the polynucleotide, a recombinant microorganism to which the recombinant vector has been introduced, a method for producing the polypeptide by means of the recombinant microorganism, and a pharmaceutical composition, for treating immune diseases or sepsis, containing the polypeptide. A polypeptide, according to the present invention, can be bound to a complement protein C5a, with higher affinity compared to being bound to a complement protein C5a receptor which is present in nature, and inhibits the activation of same, thus being widely utilized for development of formulation for preventing or treating diseases related to a complement protein C5a.
Assignee
KAIST
Country
US (United States)
Issue Date
2019-05-14
Application Date
2015-08-03
Application Number
15500921
Registration Date
2019-05-14
Registration Number
10287342
URI
http://hdl.handle.net/10203/262462
Appears in Collection
BS-Patent(특허)
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