Synergistic Ensemble of Optogenetic Actuators and Dynamic Indicators in Cell Biology

Cited 1 time in webofscience Cited 0 time in scopus
  • Hit : 166
  • Download : 0
Discovery of the naturally evolved fluorescent proteins and their genetically engineered biosensors have enormously contributed to current bio-imaging techniques. These reporters to trace dynamic changes of intracellular protein activities have continuously transformed according to the various demands in biological studies. Along with that, light-inducible optogenetic technologies have offered scientists to perturb, control and analyze the function of intracellular machineries in spatio-temporal manner. In this review, we present an overview of the molecular strategies that have been exploited for producing genetically encoded protein reporters and various optogenetic modules. Finally, in particular, we discuss the current efforts for combined use of these reporters and optogenetic modules as a powerful tactic for the control and imaging of signaling events in cells and tissues.
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Issue Date
2018-09
Language
English
Article Type
Review
Keywords

RED FLUORESCENT PROTEIN; LIVING CELLS; IN-VIVO; FRET BIOSENSORS; OPTICAL CONTROL; SPATIOTEMPORAL REGULATION; COMPLEMENTATION SYSTEM; MONOMERIC RED; BLUE-LIGHT; GREEN

Citation

MOLECULES AND CELLS, v.41, no.9, pp.809 - 817

ISSN
1016-8478
DOI
10.14348/molcells.2018.0295
URI
http://hdl.handle.net/10203/246718
Appears in Collection
BS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 1 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0