Modern buildings have become larger in scale and function, and the complexity has also increased considerably. For these reasons, there are more difficulties in evacuation and rescue when an emergency occurs, so effective evacuation methods and risk should be predicted and applied to building design, safety training, and education. We have developed an active route choice model based on human body organs and characteristics that detects risks and route conditions, communicates with neighboring occupants, determines the bottleneck point, and selects evacuation routes according to each occupant's personal characteristics. In this study, we introduce the implementation process and characteristics of the active route choice model, and by applying the model to the occupants, we compared the evacuation times according to the route condition, number of occupants, and corridor width in a virtual environment. We believe that realistic and valid results can be obtained by applying the active route choice model in crowd evacuation simulation.