Inference of Genetic Regulatory Modules Using ChIP-on-chip and mRNA Expression Data

We present here the strategy of data integration for inference of genetic regulatory modules. First, we construct all possible combinations of regulators of genes using chromatin-immunoprecipitation(ChIP)-chip data. Second, hierarchical clustering method is employed to analyze mRNA expression profiles. Third, integration method is applied to both of the data. Finally, we construct a genetic regulatory module which is involved in the function of ribosomal protein synthesis.
Publisher
한국생물정보학회
Issue Date
2007-06
Language
ENG
Citation

BIOINFORMATICS AND BIOSYSTEMS, v.2, no.2, pp.62 - 65

ISSN
1738-9798
URI
http://hdl.handle.net/10203/23484
Appears in Collection
BiS-Journal Papers(저널논문)
Files in This Item
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