Visualization and label-free quantification of microfluidic mixing using quantitative phase imaging

Microfluidic mixing plays a key role in various fields, including biomedicine and chemical engineering. To date, although various approaches for imaging microfluidic mixing have been proposed, they provide only quantitative imaging capability and require exogenous labeling agents. Quantitative phase imaging techniques, however, circumvent these problems and offer label-free quantitative information about concentration maps of microfluidic mixing. We present the quantitative phase imaging of microfluidic mixing in various types of polydimethylsiloxane microfluidic channels with different geometries; the feasibility of the present method was validated by comparing it with the results obtained by theoretical calculation based on Fick's law. (C) 2017 Optical Society of America
Publisher
OPTICAL SOC AMER
Issue Date
2017-08
Language
English
Keywords

SURFACE-PLASMON RESONANCE; RED-BLOOD-CELLS; SPECKLE PHOTOGRAPHY; WHITE-LIGHT; MICROSCOPY; INTERFEROMETRY; REFRACTOMETRY; ILLUMINATION; MICROCHANNEL; COHERENCE

Citation

APPLIED OPTICS, v.56, no.22, pp.6341 - 6347

ISSN
1559-128X
DOI
10.1364/AO.56.006341
URI
http://hdl.handle.net/10203/225830
Appears in Collection
BiS-Journal Papers(저널논문)PH-Journal Papers(저널논문)
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