Plastic bacteria? Progress and prospects for polyhydroxyalkanoate production in bacteria

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Polyhydroxyalkanoates (PHAs) are synthesized by numerous bacteria as carbon and energy storage compounds, and are good candidates for biodegradable plastic material. With the current advances in PHA research, PHA concentrations of greater than 80 g l(-1) with productivities of greater than 2 g PHA l(-1) h(-1) can be routinely obtained by fed-batch cultivation of several bacteria. Metabolic engineering approaches have been used to expand the spectrum of utilizable substrates and to improve PHA production. These advances will lower the price of PHA from the current market price of ca. US$16 kg(-1), and will allow PHA to become a leading biodegradable plastic material in the near future.
Publisher
ELSEVIER SCIENCE LONDON
Issue Date
1996-11
Language
English
Article Type
Article
Keywords

RECOMBINANT ESCHERICHIA-COLI; POLY-BETA-HYDROXYBUTYRATE; FED-BATCH CULTURE; HIGH-CELL-DENSITY; AZOTOBACTER-VINELANDII UWD; ALCALIGENES-EUTROPHUS; PSEUDOMONAS-OLEOVORANS; POLY(3-HYDROXYBUTYRIC ACID); MASS-PRODUCTION; STRAINS

Citation

TRENDS IN BIOTECHNOLOGY, v.14, no.11, pp.431 - 438

ISSN
0167-7799
URI
http://hdl.handle.net/10203/20598
Appears in Collection
CBE-Journal Papers(저널논문)
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