Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E

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Batch and continuous cultures of Mannheimia succiniciproducens MBEL55E were carried out in a complex medium containing a NaOH-treated wood hydrolysate for the production of succinic acid. The wood hydrolysate based medium was treated with NaOH before sterilization to reduce the formation of inhibitory compounds. M. succiniciproducens MBEL55E utilized xylose as well as glucose in the wood hydrolysate based medium as a carbon source for the succinic acid production. In batch cultures, the final succinic acid concentration of 11.73 g1(-1) was obtained from the pre-treated wood hydrolysate based medium, resulting in a succinic acid yield of 56% and a succinic acid productivity of 1.17 g1(-1) h(-1), while the corresponding continuous cultures gave the succinic acid yield and productivity of 55% and 3.19 g1(-1) h(-1), respectively. These results suggest that succinic acid can be produced economically and efficiently by the fermentation of M. succiniciproducens MBEL55E from an inexpensive biomass-based wood hydrolysate. (C) 2004 Elsevier Inc. All rights reserved.
Publisher
ELSEVIER SCIENCE INC
Issue Date
2004-12
Language
English
Article Type
Article; Proceedings Paper
Keywords

MANNHEIMIA-SUCCINICIPRODUCENS MBEL55E; ETHANOL-PRODUCTION; ANAEROBIOSPIRILLUM-SUCCINICIPRODUCENS; LACTIC-ACID; INHIBITION; BIOREACTOR; GLUCOSE; WHEY

Citation

ENZYME AND MICROBIAL TECHNOLOGY, v.35, pp.648 - 653

ISSN
0141-0229
URI
http://hdl.handle.net/10203/20533
Appears in Collection
CBE-Journal Papers(저널논문)
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