Enhanced Adhesion of Preosteoblasts inside 3D PCL Scaffolds by Polydopamine Coating and Mineralization

Cited 32 time in webofscience Cited 0 time in scopus
  • Hit : 486
  • Download : 0
In tissue engineering, fabrication of 3D scaffolds with well-defined, inter-connected pores followed by culture of mammalian cells is a typical approach. In practice, however, hydrophobicity of scaffold surfaces is not suitable for cells to be adhered because of poor wettability. Especially, infiltration followed by adhesion of cells inside hydrophobic scaffolds remains as a challenge. Thus, hydrophilic conversions of the surfaces regardless of surface location are critical for success. Herein, a method to enhance infiltration and adhesion of preosteoblasts inside hydrophobic poly(E-caprolactone) (PCL) scaffolds by a bio-inspired, hydroxyapatite formation is demonstrated. The approach can be a general method for controlling hydrophilicity of inner surfaces of scaffolds.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2013-10
Language
English
Article Type
Article
Keywords

GENE-EXPRESSION; POLYCAPROLACTONE SCAFFOLDS; CHONDROCYTE ADHESION; RAMAN-SPECTROSCOPY; BIOMIMETIC PROCESS; NANOFIBER MESHES; BODY-FLUIDS; BONE; HYDROXYAPATITE; SURFACES

Citation

MACROMOLECULAR BIOSCIENCE, v.13, no.10, pp.1389 - 1395

ISSN
1616-5187
DOI
10.1002/mabi.201300203
URI
http://hdl.handle.net/10203/201311
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 32 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0