Ultrafast colorimetric detection of nucleic acids based on the inhibition of the oxidase activity of cerium oxide nanoparticles

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A label-free colorimetric method to detect nucleic acids, which relies on target DNA induced shielding of the oxidase activity of CeO2 NPs, is developed. With this novel strategy, target nucleic acids can be identified within a few minutes and without the need for post-purification of PCR products.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2014-08
Language
English
Article Type
Article
Keywords

UNMODIFIED GOLD NANOPARTICLES; DNA HYBRIDIZATION; PCR; PROBES; AMPLIFICATION; SEQUENCES; ELECTROPHORESIS; DIAGNOSTICS; INFECTIONS; POLYMERASE

Citation

CHEMICAL COMMUNICATIONS, v.50, no.67, pp.9577 - 9580

ISSN
1359-7345
DOI
10.1039/c4cc03841j
URI
http://hdl.handle.net/10203/192645
Appears in Collection
CBE-Journal Papers(저널논문)
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