A Magnetic Gram Stain for Bacterial Detection

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Bacteria are often classified into Gram-positive and Gram-negative strains by staining with crystal violet (CV). The described bioorthogonal modification of CV with trans-cyclooctene (TCO) can be used to render Gram-positive bacteria magnetic with tetrazine-functionalized magnetic nanoparticles (MNP-Tz). This method allows class-specific automated magnetic detection and magnetic separation.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2012-07
Language
English
Article Type
Article
Citation

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.51, no.31, pp.7752 - 7755

ISSN
1433-7851
DOI
10.1002/anie.201202982
URI
http://hdl.handle.net/10203/192395
Appears in Collection
NT-Journal Papers(저널논문)
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