Bioinspired Surface Immobilization of Hyaluronic Acid on Monodisperse Magnetite Nanocrystals for Targeted Cancer Imaging

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Hyaluronic-acid immobilized monodisperse magnetic nanocrystals (HA-DN/MNCs) are synthesized. Dopamine, the analogue of 3,4-dihydroxy-L-phenylalanine responsible for the adhesion properties in proteins excreted by mussels, plays a key role in the surface modification of nanocrystals. HA-DN/MNCs exhibit great stability in aqueous solution, applicable for in vivo targeted-cancer imaging.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2008-11
Language
English
Article Type
Article
Keywords

BIOLOGICAL DETECTION; NANOPARTICLES; DNA; NANOWIRES; PROTEINS; DOPAMINE; DELIVERY; PROBES; ROBUST

Citation

ADVANCED MATERIALS, v.20, no.21, pp.4154 - 4154

ISSN
0935-9648
DOI
10.1002/adma.200800756
URI
http://hdl.handle.net/10203/13286
Appears in Collection
CH-Journal Papers(저널논문)EE-Journal Papers(저널논문)BS-Journal Papers(저널논문)
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