Alignment of the columnar liquid crystal phase of nano-DNA by confinement in channels

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We demonstrate that topographic confinement in micro-channels can produce aligned domains of the columnar liquid crystal phase of complementary duplex short deoxyribonucleic acid (DNA) oligomers. Optical microscopy probing birefringence and fluorescence polarisation showed that the columnar liquid crystal phase of a 1:1 mixture of the complementary dodecamers 5'-CCTCAAAACTCC-3' and 5'-GGAGTTTTGAGG-3' in aqueous solution was aligned with the duplex DNA chains oriented normal to the channel axis.
Publisher
TAYLOR & FRANCIS LTD
Issue Date
2012
Language
English
Article Type
Article
Keywords

CRYSTALLIZATION; OLIGOMERS

Citation

LIQUID CRYSTALS, v.39, no.5, pp.571 - 577

ISSN
0267-8292
DOI
10.1080/02678292.2012.666809
URI
http://hdl.handle.net/10203/101149
Appears in Collection
NT-Journal Papers(저널논문)
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